Dr. Eric S. McLamore Profile

Dr. Eric S. McLamore

Associate Professor at Clemson Univ

SPIE Involvement:

Conference Chair | Editor | Author

Area of Expertise:

Sensors , Biosensors , Fiber optics , Cell Biology

Profile Summary

Dr. McLamore specializes in the development and application of physiological sensors for bioenvironmental, agricultural, and biomedical research. Ongoing interdisciplinary research includes bioregenerative life support systems, space biology, wastewater treatment, ecotoxicology, rhizosphere-root transport, biofuels, and biomedical applications such as epilepsy, diabetes, and cancer.

Publications (16)

Proceedings Article | 14 June 2023 Presentation

Presentation

Development of an ssDNA aptamer-based electrochemical biosensor for SARS-CoV-2 Omicron detection in saliva (Conference Presentation)

Geisianny Moreira, Shoumen P. Datta, Diana Vanegas, Eric McLamore

Proceedings Volume PC12548, PC1254802 (2023) https://doi.org/10.1117/12.2663105

KEYWORDS: Biosensors, Viruses, Electrodes, Target recognition, Sodium, Proteins, Platinum, Particles, Nanoparticles, Molecules

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Proceedings Article | 8 June 2022 Presentation

Presentation

Development of an ACE-2 biosensor for point-of-need saliva diagnostics and surveillance of SARS-CoV-2

Geisianny Moreira, Lisseth Casso Hartmann, Shoumen Datta, Eric McLamore, Diana Vanegas

Proceedings Volume PC12123, PC1212303 (2022) https://doi.org/10.1117/12.2622984

KEYWORDS: Biosensors, Surveillance, Diagnostics, Surface plasmons, Proteins, Interferometry, Fiber optics, Biological research

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Proceedings Article | 16 August 2019 Presentation

Presentation

Biomimetic nanosensors for measuring pathogenic bacteria in complex food matrices (Conference Presentation)

Daniela Oliveira, Loreen Stromberg, Cicero Pola, Kshama Parate, Nicholas Cavallaro, Jonathan Claussen, Eric McLamore, Carmen Gomes

Proceedings Volume 11020, 110200J (2019) https://doi.org/10.1117/12.2519523

KEYWORDS: Pathogens, Biomimetics, Matrices, Nanosensors, Polymers, Biosensors, Sensors, Graphene, Raman spectroscopy, Bacteria

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Listeria monocytogenes and Salmonella spp. are among the most common cause of foodborne illnesses that negatively affect consumers’ health and food producers’ finances and credibility. Techniques used to detect pathogens (e.g., total viable counts, polymerase chain reaction, and enzyme-linked immunosorbent assays) are time consuming and costly as they require laboratory conditions with trained personnel. To meet this demand without compromising public health concerns, highly sensitive and rapid sensors are needed in food processing facilities for pathogen detection to reduce cost and holding time for food products. Ideally, these sensors should be small, label-free, low cost, portable, and highly sensitive/selective. This study describes some recent approaches for creating biomimetic sensors by optimizing the bacteria capture efficiency without the need for pre-concentration and pre-labeling steps. Two in-field biosensors were developed for measuring pathogenic bacteria in food matrices. The first example consists of pH-responsive polymer nanobrushes embedded with platinum nanoparticles platform with enhanced limit of detection and sensitivity for quantification of Listeria monocytogenes in fresh vegetables. A new approach using a one-step metal and polymer simultaneous deposition was tested using two pH-sensitive polymers and a thiol-terminated DNA aptamer selective to surface protein internalin A of Listeria monocytogenes. The second example demonstrates development of pathogenic biosensors for chicken broth using antibodies and DNA aptamers selective to Salmonella Typhimurium adsorbed to aerosolized graphene interdigitated electrodes (IDEs). Devices were printed in polyimide tape and aerosolized graphene was thermally annealed. The integrity of the substrate was analyzed and the nano-biosensors were characterized for topography, pH-actuation, graphene content, and electroactivity using electron microscopy, cyclic voltammetry, and multiple spectroscopy techniques (Raman, Fourier-transform infrared, and electrochemical impedance). Electrochemical impedance spectroscopy was used to evaluate the signal and determine the limit of detection by evaluating the change in charge transfer resistance. The nano-biosensors have a detection limit of approximately 5 CFU.mL-1, and a response time of approximately 17 minutes (15 minutes incubation period). The pH-sensitive nanobrushes and graphene-based biosensors have a selectivity for the target pathogen of approximately 95% in vegetable and chicken broth, respectively. The designed biosensor platform showed great potential to replace current standard methods used by the food industry for rapid foodborne pathogenic bacteria detection.

Proceedings Article | 13 May 2016 Paper

Paper

A paper based graphene-nanocauliflower hybrid composite for point of care biosensing

S. Burrs, R. Sidhu, M. Bhargava, J. Kiernan-Lewis, N. Schwalb, Y. Rong, C. Gomes, J. Claussen, D. Vanegas, E. McLamore

Proceedings Volume 9863, 98630N (2016) https://doi.org/10.1117/12.2223346

KEYWORDS: Biosensing, Graphene, Point-of-care devices, Platinum, Composites, Glucose, Raman spectroscopy, Oxides, Biosensors, Sensors

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Proceedings Article | 13 May 2016 Paper

Paper

Bio-inspired patterned networks (BIPS) for development of wearable/disposable biosensors

E. McLamore, M. Convertino, John Hondred, Suprem Das, J. Claussen, D. Vanegas, C. Gomes

Proceedings Volume 9863, 986309 (2016) https://doi.org/10.1117/12.2223345

KEYWORDS: Biosensors, Biomimetics, Fractal analysis, Electrodes, Graphene, Sensor performance, Optical lithography, Glucose, Biosensing, Electrons

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Proceedings Article | 13 May 2016 Paper

Paper

Impedance biosensor for the rapid detection of Listeria spp. based on aptamer functionalized Pt-interdigitated microelectrodes array

R. Sidhu, Y. Rong, D. Vanegas, J. Claussen, E. McLamore, C. Gomes

Proceedings Volume 9863, 98630F (2016) https://doi.org/10.1117/12.2223443

KEYWORDS: Dielectric spectroscopy, Biosensors, Bacteria, Electrodes, Pathogens, Proteins, Chemical elements, Safety, Resistance, Platinum

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Proceedings Article | 13 May 2016 Paper

Paper

Investigation of magnetic microdiscs for bacterial pathogen detection

Keisha Castillo-Torres, Nicolas Garraud, David Arnold, Eric McLamore

Proceedings Volume 9863, 98630G (2016) https://doi.org/10.1117/12.2228610

KEYWORDS: Magnetism, Ferromagnetics, Pathogens, Magnetism, Nanoparticles, Bacteria, Gold, Microfabrication, Particles, Target detection, Phase shifts

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Proceedings Article | 13 May 2016 Paper

Paper

Effect of platinum nanoparticle deposition parameters on hydrogen peroxide transduction for applications in wearable electrochemical glucose biosensors

Allison Cargill, Kathrine Neil, John Hondred, Eric McLamore, Jonathan Claussen

Proceedings Volume 9863, 98630E (2016) https://doi.org/10.1117/12.2227204

KEYWORDS: Platinum, Glucose, Electrodes, Biosensors, Sensors, Nanoparticles, Hydrogen, Carbon, Blood, Metals

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Proceedings Article | 13 May 2015 Paper

Paper

Rapid detection of listeria spp. using an internalin A aptasensor based on carbon-metal nanohybrid structures

D. Vanegas, Yue Rong, N. Schwalb, K. Hills, C. Gomes, E. McLamore

Proceedings Volume 9487, 948708 (2015) https://doi.org/10.1117/12.2177441

KEYWORDS: Electrodes, Nanomaterials, Pathogens, Bacteria, Biosensors, Graphene, Adsorption, Transducers, Sensors, Oxides

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Proceedings Article | 22 May 2014 Paper

Paper

Xanthine oxidase biosensor for monitoring meat spoilage

D. Vanegas, C. Gomes, E. McLamore

Proceedings Volume 9107, 91070V (2014) https://doi.org/10.1117/12.2050489

KEYWORDS: Biosensors, Electrodes, Nanomaterials, Platinum, Oxides, Microorganisms, Molecules, Contamination, Sensors, Graphene

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Proceedings Article | 31 May 2013 Paper

Paper

Non-invasive microsensors for studying cell/tissue physiology

D. Vanegas, M. Taguchi, P. Chaturvedi, S. Burrs, E. McLamore

Proceedings Volume 8719, 87190N (2013) https://doi.org/10.1117/12.2016233

KEYWORDS: Microsensors, Molecules, Signal to noise ratio, Sensors, Tissues, Physiology, Nanomaterials, Glucose, Oxygen, Ions

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Proceedings Article | 31 May 2013 Paper

Paper

Lignin and silicate based hydrogels for biosensor applications

S. Burrs, S. Jairam, D. Vanegas, Z. Tong, E. McLamore

Proceedings Volume 8719, 87190H (2013) https://doi.org/10.1117/12.2016285

KEYWORDS: Biosensors, Electrodes, Nanomaterials, Proteins, Graphene, Composites, Silicates, Platinum, Chemical elements, Chemistry

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Proceedings Article | 31 May 2013 Paper

Paper

A multiplexing fiber optic microsensor system for monitoring oxygen concentration in plants

P. Chaturvedi, B. Hauser, L Allen, K Boote, E. Karplus, E. McLamore

Proceedings Volume 8719, 87190O (2013) https://doi.org/10.1117/12.2015851

KEYWORDS: Oxygen, Sensors, Multiplexing, Fiber optics, Phase measurement, Microsensors, Light emitting diodes, Multiplexers, Calibration, Connectors

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Proceedings Article | 26 May 2011 Paper

Paper

Self-referencing luminescent optrodes for non-invasive, real time measurement of extracellular flux

Eric McLamore, D. Marshall Porterfield, R. Borgens, M. Banks

Proceedings Volume 8025, 802505 (2011) https://doi.org/10.1117/12.883893

KEYWORDS: Oxygen, Electrodes, Microsensors, Sensors, Diffusion, Signal to noise ratio, Time metrology, Fiber optics, Tissues, Spinal cord

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Proceedings Article | 24 April 2010 Paper

Paper

A difference imaging technique for monitoring real-time changes in morphology within the cell, tissue, and organism spatial domain

E. McLamore, M. Stensberg, G. Yale, H. Ochoa-Acuna, M. Sepulveda, X. Sun, O. Akkus, D. M. Porterfield

Proceedings Volume 7674, 76740F (2010) https://doi.org/10.1117/12.851694

KEYWORDS: Image processing, Bone, Real time imaging, Organisms, Tissues, Opacity, Physiology, Image transmission, Agriculture, Biomedical optics

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Proceedings Article | 8 May 2009 Paper

Paper

Oxygen flux as an indicator of physiological stress in aquatic organisms: a real-time biomonitoring system of water quality

Brian Sanchez, Gowri Yale, Rameez Chatni, Hugo Ochoa-Acuña, D. Marshall Porterfield, Eric Mclamore, María Sepúlveda

Proceedings Volume 7304, 730405 (2009) https://doi.org/10.1117/12.820193

KEYWORDS: Oxygen, Cyanide, Cadmium, Potassium, Organisms, Biosensing, Quality systems, Environmental sensing, Digital signal processing, Biological detection systems

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Showing 5 of 16 publications

Proceedings Volume Editor (13)

SPIE Conference Volume | 13 June 2024

Smart Biomedical and Physiological Sensor Technology XXI

SPIE Conference Volume | 25 July 2023

Smart Biomedical and Physiological Sensor Technology XX

SPIE Conference Volume | 29 June 2022

Smart Biomedical and Physiological Sensor Technology XIX

SPIE Conference Volume | 6 May 2021

Smart Biomedical and Physiological Sensor Technology XVIII

SPIE Conference Volume | 22 August 2019

Smart Biomedical and Physiological Sensor Technology XVI

Showing 5 of 13 publications

Conference Committee Involvement (14)

Smart Biomedical and Physiological Sensor Technology XXII

13 April 2025 | Orlando, Florida, United States

Smart Biomedical and Physiological Sensor Technology XXI

22 April 2024 | National Harbor, Maryland, United States

Smart Biomedical and Physiological Sensor Technology XX

1 May 2023 | Orlando, Florida, United States

Smart Biomedical and Physiological Sensor Technology XIX

4 April 2022 | Orlando, Florida, United States

Smart Biomedical and Physiological Sensor Technology XVIII

12 April 2021 | Online Only, Florida, United States

Showing 5 of 14 Conference Committees

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