17 March 2023Non-invasive monitoring of cerebral hemodynamics using near-infrared spectroscopy and diffuse correlation spectroscopy during transcatheter aortic valve replacement surgery
1Athinoula A Martinos Ctr for Biomedical Imaging (United States) 2Athinoula A. Martinos Ctr. for Biomedical Imaging (United States) 3MGH Anesthesia Research Center (United States) 4MGH Anesthesia Research Ctr. (United States) 5Massachusetts General Hospital (United States)
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Transcatheter aortic valve replacement (TAVR) surgery has a risk of cognitive impairment and neurological injury. Currently, there are few options for non-invasively monitoring brain activity and perfusion, with electroencephalography, transcranial Doppler, and near-infrared spectroscopy (NIRS) all having significant drawbacks. By combining NIRS with diffuse correlation spectroscopy (DCS) we can obtain a more complete picture of cerebral hemodynamics during TAVR procedures and examine the link to neurological outcomes. We show examples of post-valve replacement hemodynamic changes that correspond with worse/better patient outcomes
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Ailis Muldoon, Bryce Carr, Behzad Khajavi, Alyssa Martin, Mitchell Robinson, Julia Bertsch, Alexis Novak, Liza Parab, Ariel Mueller, Marissa Albanese, Jason Qu, Maria Angela Franceschini, Stefan A. Carp, "Non-invasive monitoring of cerebral hemodynamics using near-infrared spectroscopy and diffuse correlation spectroscopy during transcatheter aortic valve replacement surgery," Proc. SPIE 12364, Clinical and Translational Neurophotonics 2023, 123640F (17 March 2023); https://doi.org/10.1117/12.2668694