We report a single cell-based rapid natural killer (NK) cell activity measurement technique that utilizes a newly developed activation stimulator cocktail (ASC) along with the lens-free shadow imaging platform. The platform, i.e., Cellytics_NK, consists of compact and low-cost optoelectronic components such as LED and CMOS image sensor, and the shadow images of photographed NK cells in a disposable cell chip are analyzed within 30 seconds with an automated algorithm. The shadow parameters such as PPD and WSM have been employed to induce a combined shadow parameter (CSP) which precisely measures and distinguishes quiescent and activated NK cells (p < 0.0001).
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.