Separating scalp and brain layer hemodynamics on a single channel diffuse optical spectroscopy (Conference Presentation)

Sungchul Kim; Jae Gwan Kim

doi:10.1117/12.2546000

9 March 2020 Separating scalp and brain layer hemodynamics on a single channel diffuse optical spectroscopy (Conference Presentation)

Sungchul Kim, Jae Gwan Kim

Author Affiliations +

Proceedings Volume 11216, Multiscale Imaging and Spectroscopy; 112160K (2020) https://doi.org/10.1117/12.2546000
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Functional near-infrared spectroscopy (fNIRS) has been gaining much attention in biophotonics fields because it provides brain activity based on monitoring of hemodynamic changes. Even though fNIRS has shown significant results in brain research, the question has been raised about the origin of hemodynamic changes, due to the uncertainty of the light path in the brain structure. The goal of this study is to separate the scalp and brain layer hemodynamic by developing diffuse reflectance spectroscopy based on two-layered photon diffusion reflectance equation. In order to validate our approach, the simulation experiments were carried out. During the experiment, various tissue reflectance spectra corresponding to various hemodynamic conditions of the superficial and brain layers were generated by simulation. The results show the potential of our approach that separating brain hemodynamics from tissue reflectance spectrums.

Conference Presentation

Citation Download Citation

Sungchul Kim and Jae Gwan Kim "Separating scalp and brain layer hemodynamics on a single channel diffuse optical spectroscopy (Conference Presentation)", Proc. SPIE 11216, Multiscale Imaging and Spectroscopy, 112160K (9 March 2020); https://doi.org/10.1117/12.2546000

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available