Ms. Linpeng Lu Profile

Linpeng Lu

at Nanjing Univ of Science and Technology

SPIE Involvement:

Author

Publications (19)

Proceedings Article | 4 January 2023 Poster

Learning-based quantitative phase microscopy via a single-shot defocused intensity image with pixels aliasing

Jie Zhou, Yanbo Jin, Lingpeng Lu, Jiaji Li, Chao Zuo

Proceedings Volume PC12316, PC123160R (2023) https://doi.org/10.1117/12.2642641

KEYWORDS: Microscopy, Phase imaging, Sensors, Phase retrieval, Optical properties, Optical microscopy, Objectives, Neural networks, Medicine, Inspection

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Proceedings Article | 19 December 2022 Presentation + Paper

Lensfree single-frame phase imaging microscopy based on partially coherent LED-illumination

Yang Chen, Xuejuan Wu, Linpeng Lu, Chao Zuo

Proceedings Volume 12318, 123181I (2022) https://doi.org/10.1117/12.2642413

KEYWORDS: Holograms, Light emitting diodes, Image resolution, LED lighting, Signal to noise ratio, Optical coherence, Sensors, Phase imaging, Phase retrieval, Microscopy

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Proceedings Article | 19 December 2022 Presentation + Paper

Lens-free 3D imaging based on wavelength scanning

Xuejuan Wu, Jiasong Sun, Linpeng Lu, Yang Chen, Chao Zuo

Proceedings Volume 12318, 123181G (2022) https://doi.org/10.1117/12.2642414

KEYWORDS: Stereoscopy, Reconstruction algorithms, Tomography, Sensors, Holograms, Scattering, Microscopy, Diffraction, 3D modeling

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SPIE Journal Paper | 27 September 2022 Open Access

Hybrid brightfield and darkfield transport of intensity approach for high-throughput quantitative phase microscopy

Linpeng Lu, Jiaji Li, Yefeng Shu, Jiasong Sun, Jie Zhou, Edmund Lam, Qian Chen, Chao Zuo

AP, Vol. 4, Issue 05, 056002, (September 2022) https://doi.org/10.1117/12.10.1117/1.AP.4.5.056002

KEYWORDS: Image resolution, Diffraction, Phase retrieval, Microscopy, Light emitting diodes, Objectives, Imaging systems, Image processing, Photonics, Signal to noise ratio

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Transport of intensity equation (TIE) is a well-established non-interferometric phase retrieval approach that enables quantitative phase imaging (QPI) by simply measuring intensity images at multiple axially displaced planes. The advantage of a TIE-based QPI system is its compatibility with partially coherent illumination, which provides speckle-free imaging with resolution beyond the coherent diffraction limit. However, TIE is generally implemented with a brightfield (BF) configuration, and the maximum achievable imaging resolution is still limited to the incoherent diffraction limit (twice the coherent diffraction limit). It is desirable that TIE-related approaches can surpass this limit and achieve high-throughput [high-resolution and wide field of view (FOV)] QPI. We propose a hybrid BF and darkfield transport of intensity (HBDTI) approach for high-throughput quantitative phase microscopy. Two through-focus intensity stacks corresponding to BF and darkfield illuminations are acquired through a low-numerical-aperture (NA) objective lens. The high-resolution and large-FOV complex amplitude (both quantitative absorption and phase distributions) can then be synthesized based on an iterative phase retrieval algorithm taking the coherence model decomposition into account. The effectiveness of the proposed method is experimentally verified by the retrieval of the USAF resolution target and different types of biological cells. The experimental results demonstrate that the half-width imaging resolution can be improved from 1230 nm to 488 nm with 2.5 × expansion across a 4 × FOV of 7.19 mm2, corresponding to a 6.25 × increase in space-bandwidth product from ∼5 to ∼30.2 megapixels. In contrast to conventional TIE-based QPI methods where only BF illumination is used, the synthetic aperture process of HBDTI further incorporates darkfield illuminations to expand the accessible object frequency, thereby significantly extending the maximum available resolution from 2NA to ∼5NA with a ∼5 × promotion of the coherent diffraction limit. Given its capability for high-throughput QPI, the proposed HBDTI approach is expected to be adopted in biomedical fields, such as personalized genomics and cancer diagnostics.

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Proceedings Article | 24 November 2021 Paper

Resolution-enhanced quantitative phase imaging from transport of intensity equation: mixed-transfer-function

Linpeng Lu, Jiasong Sun, Yao Fan, Jialin Zhang, Qian Chen, Chao Zuo

Proceedings Volume 12065, 1206509 (2021) https://doi.org/10.1117/12.2601653

KEYWORDS: Modulation transfer functions, Phase imaging, Phase retrieval, Phase transfer function, Imaging systems, Deconvolution, Spatial frequencies, Microscopes, Light sources, Wigner distribution functions

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Proceedings Article | 9 October 2021 Presentation + Paper

Quantitative phase imaging with mixed-transfer-function for resolution enhancement

Linpeng Lu, Jiasong Sun, Jiaji Li, Yao Fan, Jialin Zhang, Qian Chen, Chao Zuo

Proceedings Volume 11896, 118960K (2021) https://doi.org/10.1117/12.2601160

KEYWORDS: Modulation transfer functions, Phase imaging, Phase transfer function, Resolution enhancement technologies, Phase retrieval, Imaging systems, Image resolution, Deconvolution, Spatial frequencies, Microscopes

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Proceedings Article | 9 October 2021 Paper

Super-resolution algorithm for lensless microscope based on z-axis correction

Yang Chen, Linpeng Lu, Xuejuan Wu, Jialin Zhang, Chao Zuo

Proceedings Volume 11898, 118981F (2021) https://doi.org/10.1117/12.2601263

KEYWORDS: Super resolution, Image resolution, Reconstruction algorithms, Microscopes, Diffraction, Sensors, Digital holography, Image processing, Holography

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Proceedings Article | 15 January 2021 Paper

High-frequency enhanced based on high-resolution synthetic spectrum quantitative phase imaging

Linpeng Lu, Jiasong Sun, Yao Fan, Jialin Zhang, Qian Chen, Chao Zuo

Proceedings Volume 11761, 1176110 (2021) https://doi.org/10.1117/12.2586428

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Proceedings Article | 15 January 2021 Paper

Super-resolution lensless microscopy using multi-wavelength multiplexing

Xuejuan Wu, Jialin Zhang, Jiasong Sun, Linpeng Lu, Qian Chen, Chao Zuo

Proceedings Volume 11761, 117611X (2021) https://doi.org/10.1117/12.2586569

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Proceedings Article | 15 January 2021 Paper

An improved reliability-guided phase unwrapping algorithm for digital holographic microscopic

Qian Shen, Linpeng Lu, Qian Chen, Chao Zuo

Proceedings Volume 11761, 117611D (2021) https://doi.org/10.1117/12.2586727

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Proceedings Article | 10 October 2020 Poster + Presentation + Paper

Coherence eﬀect compensation in diﬀuser-based quantitative phase imaging

Linpeng Lu, Jiasong Sun, Yao Fan, Jialin Zhang, Qian Chen, Chao Zuo

Proceedings Volume 11549, 1154918 (2020) https://doi.org/10.1117/12.2573662

KEYWORDS: Phase imaging, Coherence (optics), Speckle, Deconvolution, Image resolution

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Proceedings Article | 10 October 2020 Presentation + Paper

Lensfree super-resolved microscopy based on multi-wavelength multiplexing

Xuejuan Wu, Linpeng Lu, Jialin Zhang, Jiasong Sun, Qian Chen, Chao Zuo

Proceedings Volume 11549, 1154904 (2020) https://doi.org/10.1117/12.2573373

KEYWORDS: Microscopy, Super resolution, Microscopes

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Proceedings Article | 7 October 2020 Paper

Pixel-super-resolution lensfree microscopy based on multiple-wavelength scanning

Xuejuan Wu, Jialin Zhang, Jiasong Sun, Linpeng Lu, Qian Chen, Chao Zuo

Proceedings Volume 11571, 1157114 (2020) https://doi.org/10.1117/12.2580523

KEYWORDS: Microscopy, Super resolution, Image resolution, Reconstruction algorithms, Sensors, Image sensors, Image retrieval, Light sources, Imaging systems

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Proceedings Article | 7 October 2020 Paper

Holographic lensless quantitative phase imaging microscope

Linpeng Lu, Xiangyu Zhang, Jiasong Sun, Jialin Zhang, Yao Fan, Qian Chen, Chao Zuo

Proceedings Volume 11571, 1157111 (2020) https://doi.org/10.1117/12.2580516

KEYWORDS: Imaging systems, Microscopes, Light emitting diodes, Sensors, Phase imaging, Image resolution, 3D displays

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Proceedings Article | 7 October 2020 Paper

Lensless super-resolution imaging based on multi-wavelength illumination

Hongchen Yu, Xiangyu Zhang, LinPeng Lu, Jialin Zhang, Yuzhen Zhang

Proceedings Volume 11571, 115711A (2020) https://doi.org/10.1117/12.2581051

KEYWORDS: Super resolution, Image resolution, Light sources, Cameras, Light emitting diodes, Image restoration, Image filtering, Microscopy, Wave propagation

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Proceedings Article | 16 October 2019 Paper

Speckle quantitative phase imaging based on coherence eﬀect compensation

Linpeng Lu, Jiasong Sun, Jialin Zhang, Yao Fan, Qian Chen, Chao Zuo

Proceedings Volume 11205, 112050I (2019) https://doi.org/10.1117/12.2547856

KEYWORDS: Phase imaging, Coherence (optics), Speckle, Phase measurement, Imaging systems, Image resolution, Phase retrieval, Microscopes, Coherence imaging, Phase compensation

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Proceedings Article | 16 October 2019 Paper

Speckle quantitative phase imaging camera based on the transport of intensity equation

Linpeng Lu, Jiasong Sun, Jialin Zhang, Yao Fan, Qian Chen, Chao Zuo

Proceedings Volume 11205, 1120521 (2019) https://doi.org/10.1117/12.2547879

KEYWORDS: Speckle, Phase imaging, Cameras, Microscopes, Diffusers, Microlens array, Distortion, Coherence imaging, Wigner distribution functions, Phase measurement

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