Dr. Michael A. Wayne Profile

Dr. Michael A. Wayne

at EPFL

SPIE Involvement:

Author

Publications (6)

Proceedings Article | 20 June 2024 Presentation

Towards Surface-Correction of Deep-Tissue Blood Flow Dynamics with Massively Parallelized Diffuse Correlation Spectroscopy

Lucas Kreiss, Melissa Wu, Michael Wayne, Shiqi Xu, Paul McKee, Derrick Dwamena, Kyle Cowdrick, Erin Buckley, Claudio Bruschini, Edoardo Charbon, Scott Huettel, Roarke Horstmeyer

Proceedings Volume PC13007, PC1300708 (2024) https://doi.org/10.1117/12.3022813

KEYWORDS: Blood circulation, Spectroscopy, Source detector separation, Diffusion, Cognitive modeling, Data modeling, Cerebral blood flow, Autocorrelation, Tissues, Statistical analysis

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Proceedings Article | 13 March 2024 Presentation

Deep blood flow extraction for diffuse correlation spectroscopy at photon-starved regimes using SPAD arrays

Melissa Wu, Lucas Kreiss, Michael Wayne, Mitchell Robinson, Claudio Bruschini, Edoardo Charbon, Roarke Horstmeyer

Proceedings Volume PC12841, PC128410B (2024) https://doi.org/10.1117/12.3001940

KEYWORDS: Spectroscopy, Blood circulation, Speckle, Autocorrelation, Source detector separation, Tissue optics, Optical spectroscopy, Nervous system, In vivo imaging, Fluorescence correlation spectroscopy

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Proceedings Article | 13 March 2024 Presentation + Paper

SwissSPAD2/3: a family of natively digital, time gated SPAD cameras with continuous streaming at up to 100 kpfs and picosecond system-level synchronization for quantum imaging applications

Paul Mos, Michael Wayne, Andrei Ardelean, Arin Ulku, Edoardo Charbon, Claudio Bruschini

Proceedings Volume 12912, 129120Q (2024) https://doi.org/10.1117/12.2692931

KEYWORDS: Field programmable gate arrays, Single photon avalanche diodes, Binary data, Picosecond phenomena, Sensors, Quantum gates, Cameras, Imaging systems, Digital cameras, Quantum imaging

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Proceedings Article | 8 March 2024 Presentation + Paper

Piccolo gated: a CMOS 32x32 SPAD camera with all-solid-state nanosecond time gating and PCIe readout for single-photon time-domain DCS and near-infrared optical tomography

Paul Mos, Scott Lindner, Chao Zhang, Michael Wayne, Tommaso Milanese, Claudio Bruschini, Edoardo Charbon

Proceedings Volume 12895, 1289507 (2024) https://doi.org/10.1117/12.2692934

KEYWORDS: Single photon avalanche diodes, Field programmable gate arrays, Quantum sensors, Time correlated single photon counting, Sensors, Optical tomography, Quantum correlations, Picosecond phenomena, Signal detection, Quantum gates

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The Piccolo gated sensor features a 32x32 SPAD array of single-photon avalanche diodes (SPADs) operating in time-correlated single-photon counting (TCSPC). The chip enables event-driven readout and a maximum count rate of 220 Mcps. The sensor is based on the original Piccolo architecture, whereas the pixel was redesigned to accommodate a sub-nanosecond time gating circuitry. As a result, the pitch was increased by 3 μm to 31 μm with a slightly lower fill factor of 23.7%. The time-gating circuitry comprises active recharge to activate the gate and a fast switch to de-activate the SPAD. The sensor is equipped with 128 dynamically allocated, 50 ps time-to-digital converters (TDCs) at the bottom of the array. Four TDCs are shared among 32 SPADs in each column, where a mechanism of reallocation is used to optimize the use of TDCs and to minimize photon loss. Time gating can reduce both uncorrelated and correlated noise by reducing overall active time and by increasing relaxation time after detection, respectively. Upon acquisition of TCSPC data, the FPGA reorganizes it in histograms, which may be dynamically allocated and reduced in the number of bins to optimize memory use and data transfer from the FPGA to an external Mac/PC. The TDCs may also be calibrated to suppress differential and integral nonlinearities on-FPGA. Timestamps are stored in DDR3 and streamed out of the FPGA through PCIe with a data rate of 5.12 Gbps. Thanks to these techniques, the maximum count rate of the sensor was increased by about 3×. The time gating feature was implemented to extend dynamic range, and therefore depth, of near-infrared optical tomography (NIROT) and g(2) multi-depth time-domain diffuse correlation spectroscopy (TD-mDCS). Time gating is especially useful in NIROT and mDCS, as it helps suppress large numbers of early photons reflected back from the sample’s surface, e.g. the skull or skin. Thus, the Piccolo-gated architecture could show its suitability in these imaging modality.

Proceedings Article | 25 April 2023 Presentation + Paper

NIR fluorescence lifetime macroscopic imaging with a novel time-gated SPAD camera

Xavier Michalet, Arin Ulku, Michael Wayne, Shimon Weiss, Claudio Bruschini, Edoardo Charbon

Proceedings Volume 12384, 1238409 (2023) https://doi.org/10.1117/12.2649227

KEYWORDS: Fluorescence lifetime imaging, Gated imaging, Single photon avalanche diodes, Fluorescence, Near infrared, Dyes, Pulsed laser operation

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Proceedings Article | 11 July 2021 Poster + Presentation + Paper

Towards quantum 3D imaging devices

Gianlorenzo Massaro, Cristoforo Abbattista, Leonardo Amoruso, Samuel Burri, Edoardo Charbon, Francesco Di Lena, Augusto Garuccio, Davide Giannella, Zdeněk Hradil, Michele Iacobellis, Paul Mos, Libor Motka, Martin Paùr, Francesco V. Pepe, Michal Peterek, Isabella Petrelli, Jaroslav Řeháček, Francesca Santoro, Francesco Scattarella, Arin Ulku, Sergii Vasiukov, Michael Wayne, Milena D'Angelo, Claudio Bruschini, Maria Ieronymaki, Bohumil Stoklasa

Proceedings Volume 11844, 1184410 (2021) https://doi.org/10.1117/12.2600791

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Showing 5 of 6 publications

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