Fiber optic glucose biosensor

Ignacio Del Villar; Ignacio R. Matias; Francisco J. Arregui; Jesús M. Corres

doi:10.1117/1.2360174

1 October 2006 Fiber optic glucose biosensor

Ignacio Del Villar, Ignacio R. Matias, Francisco J. Arregui, Jesús M. Corres

Author Affiliations +

Optical Engineering, Vol. 45, Issue 10, 104401 (October 2006). https://doi.org/10.1117/1.2360174

Abstract

A fiber-optic biosensor for glucose concentration detection has been designed, based on electrostatic self-assembly. The end face of a multimode fiber is coated with poly(allylamine hydrochloride) in combination with Prussian blue and the enzyme glucose oxidase. The glucose concentration that can be measured ranges between 0.06 and 2 mM. The initial velocity of change of the output biosensor signal has been found to be linear in the glucose concentration. The sensor recovers after immersion in ascorbic acid. The pH values analyzed range between 5 and 7. The sensitivity of the device has been increased by adjusting the number of bilayers and by adding some capping bilayers at the end of the structure.

©(2006) Society of Photo-Optical Instrumentation Engineers (SPIE)

Citation Download Citation

Ignacio Del Villar, Ignacio R. Matias, Francisco J. Arregui, and Jesús M. Corres "Fiber optic glucose biosensor," Optical Engineering 45(10), 104401 (1 October 2006). https://doi.org/10.1117/1.2360174

Published: 1 October 2006

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available