CONFERENCE PROCEEDINGS
Advanced Search
Home > Journals > J. Biomed. Opt. > Volume 17 > Issue 12 > Article
Open Access
3 December 2012 Complex conjugate artifact-free adaptive optics optical coherence tomography of in vivo human optic nerve head
Dae Yu Kim, John S. Werner, Robert J. Zawadzki
Author Affiliations +
Journal of Biomedical Optics, Vol. 17, Issue 12, 126005 (December 2012). https://doi.org/10.1117/1.JBO.17.12.126005
Abstract
We acquired in vivo images of the human optic nerve head (ONH) using an adaptive optics—optical coherence tomography (AO-OCT) system. In order to improve imaging of the lamina cribrosa in the ONH with high lateral resolution and sensitivity, we implemented a complex conjugate artifact-free Fourier domain OCT (Fd-OCT) acquisition scheme with a reference arm-based phase shifting method. This allowed positioning of the lamina cribrosa structures near the zero path length difference where AO-OCT imaging achieves highest sensitivity. Implementation of our complex conjugate artifact removal (CCR) method required constant phase shifts between consecutive axial scans (A-scans), generated by continuous beam path-length changes from offsetting the pivot point of the scanning mirror placed in the reference arm. Fourier transform along the transverse axis and a filtering algorithm allowed reconstruction of CCR AO-OCT images. The suppression ratio of the mirror artifact was approximately 22 dB (at 18,000 A-scans per second acquisition speed) with a paperboard test target and an optimum phase-shift value. Finally, we reconstructed the three-dimensional structure of human ONH with enhanced depth range and sensitivity using CCR AO-OCT.
© 2012 Society of Photo-Optical Instrumentation Engineers (SPIE) 0091-3286/2012/$25.00 © 2012 SPIE
Citation Download Citation
Dae Yu Kim, John S. Werner, and Robert J. Zawadzki "Complex conjugate artifact-free adaptive optics optical coherence tomography of in vivo human optic nerve head," Journal of Biomedical Optics 17(12), 126005 (3 December 2012). https://doi.org/10.1117/1.JBO.17.12.126005
Published: 3 December 2012
JOURNAL ARTICLE
 6 PAGES
DOWNLOAD PAPER SAVE TO MY LIBRARY
GET CITATION
Lens.org Logo
CITATIONS
Cited by 12 scholarly publications.
Advertisement
Advertisement
RIGHTS & PERMISSIONS
Get copyright permission  Get copyright permission on Copyright Marketplace
KEYWORDS
Adaptive optics optical coherence tomography
In vivo imaging
Mirrors
Optical coherence tomography
Optic nerve
Head
Eye
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top