Noninvasive near infrared optical imaging of human brain function with subsecond temporal resolution

Monica Fabiani; Gabriele Gratton; Paul M. Corballis

doi:10.1117/12.251031

1 October 1996 Noninvasive near infrared optical imaging of human brain function with subsecond temporal resolution

Monica Fabiani, Gabriele Gratton, Paul M. Corballis

Author Affiliations +

Journal of Biomedical Optics, Vol. 1, Issue 4, (October 1996). https://doi.org/10.1117/12.251031

Abstract

Our understanding of human brain function can clearly benefit from neurophysiological techniques capable of providing dynamic maps of activity. A series of studies is reviewed indicating that noninvasive nearinfrared optical imaging methods can provide a unique combination of spatial and temporal resolution that could be used to derive dynamic maps of human brain activity. The noninvasive NIR optical data reviewed are based on the frequency-domain time-resolved measurement of photon migration parameters (intensity and delay) through brain tissue. These measurements are taken through the intact surface of the head. With these methods, two distinct components of the optical response can be identified: the ‘‘slow optical signal’’ (2–10 s latency), presumably due to hemodynamic and metabolic changes, and the ‘‘fast optical signal’’ (or event-related optical response) occurring as early as 50 to 100 ms from stimulation, and probably due to neuronal activation.

Citation Download Citation

Monica Fabiani, Gabriele Gratton, and Paul M. Corballis "Noninvasive near infrared optical imaging of human brain function with subsecond temporal resolution," Journal of Biomedical Optics 1(4), (1 October 1996). https://doi.org/10.1117/12.251031

Published: 1 October 1996

Access the abstract

JOURNAL ARTICLE
12 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

CITATIONS

Cited by 17 scholarly publications.

Explore citations on Lens.org

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Brain

Tissue optics

Neuroimaging

Scattering

Near infrared

Optical imaging

Temporal resolution

Show All Keywords

RELATED CONTENT

A radiative transfer equation based image reconstruction method incorporating boundary...
Proceedings of SPIE (March 13 2017)

Optical imaging characterizing brain response to thermal insult in injured...
Proceedings of SPIE (February 08 2018)

Optical topographic reconstruction using photon measurement density function
Proceedings of SPIE (November 02 2001)

Phantom experiment on relationship between activated position of cerebral cortex...
Proceedings of SPIE (June 29 2001)

Effect of fiber arrangement on spatial resolution of near infrared...
Proceedings of SPIE (October 15 2003)

Laser-induced photoacoustic tomography enhanced with an optical contrast agent
Proceedings of SPIE (July 12 2004)

Optical imaging of physiological processes in the human brain ...
Proceedings of SPIE (March 04 1999)

Subscribe to Digital Library

Receive Erratum Email Alert

Show All Keywords

Keywords/Phrases

Search In:

Publication Years