CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume PC13010 > Article
Presentation
19 June 2024 Microbeads accelerate gellation in 3D collagen hydrogels
Remy Avila, Laura Rodríguez-Mandujano, Reinher Pimentel-Domínguez, Elisa V. Tamariz, Astrid L. Giraldo-Betancur, Edgar Campos-Puente
Author Affiliations +
Proceedings Volume PC13010, Tissue Optics and Photonics III; PC1301007 (2024) https://doi.org/10.1117/12.3022672
Event: SPIE Photonics Europe, 2024, Strasbourg, France
Abstract
Collagen type I is extensively employed in 3D cell culture and tissue engineering.This research investigates the impact of embedded microbeads of different types on the fibrillogenesis process in collagen type I hydrogels. Our findings reveal that the presence of microbeads within the collagen matrix alters the fibrillogenesis dynamics. Specifically, carboxylated fluorescent microbeads accelerate gelation by 3.6 times, while silica microbeads decelerate collagen fibril formation by a factor of 1.9, in comparison to pure collagen hydrogels. These observations suggest that carboxylate microbeads serve as nucleation sites, influencing the binding of early collagen fibrils to the microbeads.
Conference Presentation
© (2024) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Remy Avila, Laura Rodríguez-Mandujano, Reinher Pimentel-Domínguez, Elisa V. Tamariz, Astrid L. Giraldo-Betancur, and Edgar Campos-Puente "Microbeads accelerate gellation in 3D collagen hydrogels", Proc. SPIE PC13010, Tissue Optics and Photonics III, PC1301007 (19 June 2024); https://doi.org/10.1117/12.3022672
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Collagen
Hydrogels
Confocal microscopy
Fabrication
Matrices
Nanofibers
Reflectivity
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top