Miniaturized handheld laser speckle contrast imaging for evaluating parathyroid glands viability

Han Dong; Parker A. Willmon; Sean T. Fitzgerald; Emmanuel A. Mannoh; Carmen C. Solórzano; Anita Mahadevan-Jansen

doi:10.1117/12.3011340

13 March 2024 Miniaturized handheld laser speckle contrast imaging for evaluating parathyroid glands viability

Han Dong, Parker A. Willmon, Sean T. Fitzgerald, Emmanuel A. Mannoh, Carmen C. Solórzano, Anita Mahadevan-Jansen

Proceedings Volume PC12818, Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2024; (2024) https://doi.org/10.1117/12.3011340
Event: SPIE BiOS, 2024, San Francisco, California, United States

Conference Poster

Abstract

Laser speckle contrast imaging (LSCI) is a contrast-free optical method offering quantitative assessment of superficial blood vessel vascularity. Its clinical significance is evident in intraoperative scenarios, particularly for assessing parathyroid gland viability in thyroid surgery. Despite notable sensitivity and specificity, conventional overhead LSCI methods, characterized by bulky designs, present integration challenges in surgical procedures. To address these limitations, we developed a miniaturized handheld LSCI probe, enhancing portability and maneuverability. A validation assessment compared the handheld system with an overhead LSCI setup for detecting vascularity in parathyroid glands in parathyroidectomy surgeries. Results from comparisons with the established overhead LSCI system, combined with evaluations by an experienced surgeon, underscore the handheld LSCI system's effectiveness in human parathyroid gland vascularity classification. This study's findings offer valuable insights into the performance and clinical utility of the newly developed miniaturized handheld LSCI system.

Citation Download Citation

Han Dong, Parker A. Willmon, Sean T. Fitzgerald, Emmanuel A. Mannoh, Carmen C. Solórzano, and Anita Mahadevan-Jansen "Miniaturized handheld laser speckle contrast imaging for evaluating parathyroid glands viability", Proc. SPIE PC12818, Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2024, (13 March 2024); https://doi.org/10.1117/12.3011340

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