Multifocal metasurface optics for rapid virtual biopsy of cellular-resolution optical coherence tomography (Conference Presentation)

Jing J. Zhao; Aidan Van Vleck; Yonatan Winetraub; Lin Du; Yong Han; Adam de la Zerda

doi:10.1117/12.2653933

16 March 2023 Multifocal metasurface optics for rapid virtual biopsy of cellular-resolution optical coherence tomography (Conference Presentation)

Jing J. Zhao, Aidan Van Vleck, Yonatan Winetraub, Lin Du, Yong Han, Adam de la Zerda

Author Affiliations +

Proceedings Volume PC12390, High-Speed Biomedical Imaging and Spectroscopy VIII; PC123900V (2023) https://doi.org/10.1117/12.2653933
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Cellular resolution of optical coherence tomography (OCT) is vital to achieve precise diagnosis by offering high-quality images of virtual biopsy. Currently, the common solution is to apply dynamic focusing to axially translate the focus through the region of interest with a high numerical aperture (N.A.) objective, followed by Z-stacking to rebuild a high-resolution 3D volume. To accelerate the imaging acquisition, this work developed metasurface optical plates to generate multiple foci along axial direction. Two-/three-/seven-foci had been testified with bead phantom using a scanning OCT. Human skin and human brain samples were imaged with cellular resolution.

Conference Presentation

Citation Download Citation

Jing J. Zhao, Aidan Van Vleck, Yonatan Winetraub, Lin Du, Yong Han, and Adam de la Zerda "Multifocal metasurface optics for rapid virtual biopsy of cellular-resolution optical coherence tomography (Conference Presentation)", Proc. SPIE PC12390, High-Speed Biomedical Imaging and Spectroscopy VIII, PC123900V (16 March 2023); https://doi.org/10.1117/12.2653933

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