High-grade cervical intraepithelial neoplasia treatment comparing two photodynamic therapy protocols

Natalia M. Inada; Cynthia A. de Castro; Carolina F. da Silva; Welington Lombardi M.D.; Vanderlei  S. Bagnato

doi:10.1117/12.2647382

27 March 2023 High-grade cervical intraepithelial neoplasia treatment comparing two photodynamic therapy protocols

Natalia M. Inada, Cynthia A. de Castro, Carolina F. da Silva, Welington Lombardi M.D., Vanderlei S. Bagnato

Proceedings Volume PC12369, Optics and Biophotonics in Low-Resource Settings IX; PC123690I (2023) https://doi.org/10.1117/12.2647382
Event: SPIE BiOS, 2023, San Francisco, California, United States

Conference Poster

Abstract

Photodynamic therapy (PDT) is a therapeutical modality which offers a minimally invasive alternative for high-grade cervical intraepithelial neoplasia (CIN) treatment. This prospective randomized controlled clinical trial aims to compare two PDT protocols for the treatment of histopathologically similar high-grade CIN. The patients were followed 60 days and two years after the treatment by cytology, hybrid capture and pathology analysis after the Excision of Transformation Zone (ETZ). Preliminary results are indicating, after two years follow-up, that combining ecto and endocervix treatment leads to better cure rates of high-grade CIN.

Citation Download Citation

Natalia M. Inada, Cynthia A. de Castro, Carolina F. da Silva, Welington Lombardi M.D., and Vanderlei S. Bagnato "High-grade cervical intraepithelial neoplasia treatment comparing two photodynamic therapy protocols", Proc. SPIE PC12369, Optics and Biophotonics in Low-Resource Settings IX, PC123690I (27 March 2023); https://doi.org/10.1117/12.2647382

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