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4 March 2022 Development of dyes/tracers for the analysis of different kidney functions.
Srishti Vajpayee, Norbert Gretz, Rossana Perciaccante, Rosalinde Masereeuw, Tim Devling, Mohammed Mohiuddin Yusuf, Yinuo Xie, James Littlewood, João Faria, Tiziana Picascia
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Proceedings Volume PC11979, Frontiers in Biological Detection: From Nanosensors to Systems XIV; PC119790A (2022) https://doi.org/10.1117/12.2606878
Event: SPIE BiOS, 2022, San Francisco, California, United States
Abstract
GFR is till date the most used parameter for diagnosing kidney diseases. Nevertheless, tubular secretion and reabsorption play an equally important role in healthy functioning of the kidney. The primary focus of this study is to synthesise novel fluorescent markers for evaluating the three physiological processes of the kidney. This would help diagnosing function-/location-specific abnormality in kidney. Since the ideal goal would be to measure all the kidney parameters altogether using a transcutaneous device, the absorbance and emission wavelength for each marker is designed to be significantly different. This paves way for a wholesome, rapid, and non-invasive technique for kidney diagnosis.
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Srishti Vajpayee, Norbert Gretz, Rossana Perciaccante, Rosalinde Masereeuw, Tim Devling, Mohammed Mohiuddin Yusuf, Yinuo Xie, James Littlewood, João Faria, and Tiziana Picascia "Development of dyes/tracers for the analysis of different kidney functions.", Proc. SPIE PC11979, Frontiers in Biological Detection: From Nanosensors to Systems XIV, PC119790A (4 March 2022); https://doi.org/10.1117/12.2606878
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KEYWORDS
Kidney
Absorbance
Diagnostics
Electromagnetism
Fluorescent markers
Light emitting diodes
Visible radiation
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