Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution

S. I. Shopova; R. Rajmangal; S. Holler; S. Arnold

doi:10.1117/12.920614

19 May 2012 Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution

S. I. Shopova, R. Rajmangal, S. Holler, S. Arnold

Author Affiliations +

Proceedings Volume 8376, Photonic Microdevices/Microstructures for Sensing IV; 837605 (2012) https://doi.org/10.1117/12.920614
Event: SPIE Defense, Security, and Sensing, 2012, Baltimore, Maryland, United States

Abstract

We describe and demonstrate a physical mechanism that substantially enhances the label-free sensitivity of a Whispering-Gallery-Mode biosensor for the detection of individual nanoparticles in aqueous solution. It involves the interaction of dielectric nanoparticle in an equatorial carousel orbit with a plasmonic nanoparticle bound on the orbital path. As a 60 nm dielectric particle parks on plasmonic hot spots we observe frequency shifts that are considerably enhanced consistent with a simple reactive model. Using the same model the label free detection of a single bovine serum albumin (BSA) molecule is projected.

Citation Download Citation

S. I. Shopova, R. Rajmangal, S. Holler, and S. Arnold "Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution", Proc. SPIE 8376, Photonic Microdevices/Microstructures for Sensing IV, 837605 (19 May 2012); https://doi.org/10.1117/12.920614

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