In vivo determination of absorption and scattering properties in rat cerebral cortex using single reflectance fiber probe with two sourcecollector geometries

Izumi Nishidate; Satoko Kawauchi; Shunichi Sato; Miya Ishihara; Makoto Kikuchi; Manabu Sato

doi:10.1117/12.889659

16 June 2011 In vivo determination of absorption and scattering properties in rat cerebral cortex using single reflectance fiber probe with two sourcecollector geometries

Izumi Nishidate, Satoko Kawauchi, Shunichi Sato, Miya Ishihara, Makoto Kikuchi, Manabu Sato

Author Affiliations +

Proceedings Volume 8087, Clinical and Biomedical Spectroscopy and Imaging II; 80872P (2011) https://doi.org/10.1117/12.889659
Event: European Conferences on Biomedical Optics, 2011, Munich, Germany

Abstract

We present a new method determining the absorption coefficients and the reduced scattering coefficients of in vivo rat cerebral cortex using single reflectance fiber probe with two source-collector geometries. Experiments with optical phantoms were conducted to evaluate the performance of the proposed fiber probe system. In order to confirm the possibility of the method to evaluate changes in the optical properties of cerebral cortex, we performed in vivo experiments for exposed rat brain during CSD evoked by the pinprick stimulation.

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Izumi Nishidate, Satoko Kawauchi, Shunichi Sato, Miya Ishihara, Makoto Kikuchi, and Manabu Sato "In vivo determination of absorption and scattering properties in rat cerebral cortex using single reflectance fiber probe with two sourcecollector geometries", Proc. SPIE 8087, Clinical and Biomedical Spectroscopy and Imaging II, 80872P (16 June 2011); https://doi.org/10.1117/12.889659

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