Clinical translation of ultraviolet autofluorescence microscopy towards endomicroscopy for early detection of cancer

Bevin Lin; Shiro Urayama; Ramez M. G. Saroufeem; Dennis L. Matthews; Stavros G. Demos

doi:10.1117/12.888682

3 January 2011 Clinical translation of ultraviolet autofluorescence microscopy towards endomicroscopy for early detection of cancer

Bevin Lin, Shiro Urayama, Ramez M. G. Saroufeem, Dennis L. Matthews, Stavros G. Demos

Author Affiliations +

Proceedings Volume 7990, Optical Sensors and Biophotonics II; 799002 (2011) https://doi.org/10.1117/12.888682
Event: Asia Communications and Photonics Conference and Exhibition, 2010, Shanghai, Shanghai, China

Abstract

The non-invasiveness of autofluorescence technology may reduce sampling error and time delay for histopathology diagnosis. We establish biophotonic methods and guidelines to visualize and interpret early epithelial tissue changes that signify disease. Flexible and rigid fiber endomicroscopy instrumentation design parameters feasible for translation towards clinical use are in development.

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Bevin Lin, Shiro Urayama, Ramez M. G. Saroufeem, Dennis L. Matthews, and Stavros G. Demos "Clinical translation of ultraviolet autofluorescence microscopy towards endomicroscopy for early detection of cancer", Proc. SPIE 7990, Optical Sensors and Biophotonics II, 799002 (3 January 2011); https://doi.org/10.1117/12.888682

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KEYWORDS

Atrial fibrillation

Tissues

Endomicroscopy

Ultraviolet radiation

Microscopy

Image filtering

Imaging systems

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