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In this presentation we report our results of investigation of anisoplanatism effect in human eye. We measured aberrations of human eye depending on the location of beacon source on the retina and determined the value of the isoplanatic patch. We show that the size of isoplanatic patch depends on the direction of compensation and determine an optimal direction for every patient. To enhance quality of retina image correction we introduce lamellar eye model where aberrations of human eye are considered to be induced in two thin phase screens corresponding to cornea and crystal lens locations. For that model we found the optimal corrector location which differs from the one for the one-layer eye model.
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