Measurement system for noninvasive dynamic optical topography

Yuichi Yamashita; Atsushi Maki; Hideaki Koizumi

doi:10.1117/12.356816

15 July 1999 Measurement system for noninvasive dynamic optical topography

Yuichi Yamashita, Atsushi Maki, Hideaki Koizumi

Proceedings Volume 3597, Optical Tomography and Spectroscopy of Tissue III; (1999) https://doi.org/10.1117/12.356816
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

We have developed a 24-channel simultaneous measurement system for optical topography that noninvasively obtains dynamic images of brain activity over a measurement area of 90 mm by 90 mm. To evaluate the system performance, we utilized a phantom containing a rotating absorber in a cylindrical scattering medium. In this system, eight incident and eight detecting optical fibers are arranged alternately at points of a square lattice on the phantom. The phantom is illuminated with light of two wavelengths (780 and 830 nm) from each incident fiber. Reflected light is received by the detecting fibers, each of which is connected to an avalanche photodiode. Multiple modulation and lock-in detection are used to enable highly sensitive measurement with negligible crosstalk (less than -50 dB). In the phantom measurement, we obtained topographic dynamic images of the absorber rotating in the medium with a temporal resolution of 0.5 s.

Citation Download Citation

Yuichi Yamashita, Atsushi Maki, and Hideaki Koizumi "Measurement system for noninvasive dynamic optical topography", Proc. SPIE 3597, Optical Tomography and Spectroscopy of Tissue III, (15 July 1999); https://doi.org/10.1117/12.356816

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