Development of near-infrared spectroscopy for monitoring cerebral regional blood oxygenation and volume in the human newborn

H. P. Lehr; Yappa A.B.D. Wickramasinghe; Peter J. Rolfe

doi:10.1117/12.280225

18 August 1997 Development of near-infrared spectroscopy for monitoring cerebral regional blood oxygenation and volume in the human newborn

H. P. Lehr, Yappa A.B.D. Wickramasinghe, Peter J. Rolfe

Author Affiliations +

Proceedings Volume 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II; (1997) https://doi.org/10.1117/12.280225
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

Human newborns can suffer from neuro-developmental abnormalities, when they are born as preterms. With near infrared spectroscopy (NIRS) it is possible to investigate any brain disease occurring together with these neuro- abnormalities. The specific absorption properties of haemoglobin and oxygenated haemoglobin in the near infrared region allow to measure the oxygenation status and several other variables. Local variations in cerebral blood volume (CBV) and blood oxygenation is important for a better understanding of these abnormalities.

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H. P. Lehr, Yappa A.B.D. Wickramasinghe, and Peter J. Rolfe "Development of near-infrared spectroscopy for monitoring cerebral regional blood oxygenation and volume in the human newborn", Proc. SPIE 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, (18 August 1997); https://doi.org/10.1117/12.280225

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