Laser-induced fluorescence spectroscopy of human normal and cancerous tissues

Weimin Chen; Bin He; Guang Hui Wei; Ge Gao; Shirong Li

doi:10.1117/12.251948

23 September 1996 Laser-induced fluorescence spectroscopy of human normal and cancerous tissues

Weimin Chen, Bin He, Guang Hui Wei, Ge Gao, Shirong Li

Author Affiliations +

Proceedings Volume 2887, Lasers in Medicine and Dentistry: Diagnostics and Treatment; (1996) https://doi.org/10.1117/12.251948
Event: Photonics China '96, 1996, Beijing, China

Abstract

Fluorescence properties of stomach tissues have been investigated to determine whether malignant specimens can be discriminated in vitro. Differences between normal and tumor tissues are found that concern both the intensity distribution and spectral shape of the autofluorescence emission. According to the distinctions tumor tissues would be differed from the normal tissues. The resulting spectra could be differentiate histologically stomach abnormal tissues from normal tissues with a sensitivity and specificity value of 90 percent and 92 percent. Furthermore, fluorescence spectra from human stomach normal and malignant tissues have been measured in real time in vivo.

Citation Download Citation

Weimin Chen, Bin He, Guang Hui Wei, Ge Gao, and Shirong Li "Laser-induced fluorescence spectroscopy of human normal and cancerous tissues", Proc. SPIE 2887, Lasers in Medicine and Dentistry: Diagnostics and Treatment, (23 September 1996); https://doi.org/10.1117/12.251948

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