Autofluorescence of normal and tumor mucosa of human colon: a comprehensive analysis

Giovanni F. Bottiroli; Renato Marchesini; Anna Cleta Croce; Marco Dal Fante; Carolina Cuzzoni; Silvana Di Palma; Pasquale Spinelli

doi:10.1117/12.151183

27 August 1993 Autofluorescence of normal and tumor mucosa of human colon: a comprehensive analysis

Giovanni F. Bottiroli, Renato Marchesini, Anna Cleta Croce, Marco Dal Fante, Carolina Cuzzoni, Silvana Di Palma, Pasquale Spinelli

Author Affiliations +

Proceedings Volume 1887, Physiological Imaging, Spectroscopy, and Early-Detection Diagnostic Methods; (1993) https://doi.org/10.1117/12.151183
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

Both 'in vivo' and 'ex vivo' spectrofluorometric studies of neoplastic and non-neoplastic mucosa of human colon have been carried out, in order to verify the potentials of tissue natural fluorescence as a possible parameter to distinguish normal from diseased tissues, Spectrofluorometric analysis performed at colonoscopy on patients affected by neoplasia, showed that adenocarcinoma, adenoma and non-neoplastic mucosa differ in the fluorescence emissions. The results have been interpreted according to the data obtained on cryostatic sections from biopsies by means of a microspectrofluorometric analysis carried out on each histological component.

Citation Download Citation

Giovanni F. Bottiroli, Renato Marchesini, Anna Cleta Croce, Marco Dal Fante, Carolina Cuzzoni, Silvana Di Palma, and Pasquale Spinelli "Autofluorescence of normal and tumor mucosa of human colon: a comprehensive analysis", Proc. SPIE 1887, Physiological Imaging, Spectroscopy, and Early-Detection Diagnostic Methods, (27 August 1993); https://doi.org/10.1117/12.151183

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