Human expiration content diagnostics by tunable diode lasers in middle infrared

Andrian I. Kouznetsov; Konstantin L. Moskalenko; Alexander I. Nadezhdinskii; Eugene V. Stepanov

doi:10.1117/12.58677

1 April 1992 Human expiration content diagnostics by tunable diode lasers in middle infrared

Andrian I. Kouznetsov, Konstantin L. Moskalenko, Alexander I. Nadezhdinskii, Eugene V. Stepanov

Proceedings Volume 1724, Tunable Diode Laser Applications; (1992) https://doi.org/10.1117/12.58677
Event: Tunable Diode Laser Applications, 1993, Moscow, Russian Federation

Abstract

Results on the application of tunable diode laser gas analysis to determining the trace components of human breath are presented. Schemes of the analyzers specially developed for measurement of both carbon oxides in expiration are described. A few results illuminating possible applications of TDL in high sensitive medical diagnostics have been obtained. For nonsmokers, the expired concentration of CO is slightly higher than inhaled air. Specific surplus value depends on the person's age. The surplus CO content increased significantly just after intensive physical exercises like jogging. For smokers, the farmacokinetical curve of abundant CO removal from the organism could be investigated. The smoking status of tested individuals becomes easy available. Breath-hold simultaneous measurements of CO and CO₂ have shown the difference in the dependencies of their concentrations on breath-holding time. The possibility to investigate phenomena like molecular pulmonary diffusion of the alveolar-capillary membrane and an organism's compensation reactions to oxygen shortage seems to become real. Perspective leads for development and the application of diode laser spectroscopy methods to the analysis of gaseous microimpurities in medicine are also discussed.

Citation Download Citation

Andrian I. Kouznetsov, Konstantin L. Moskalenko, Alexander I. Nadezhdinskii, and Eugene V. Stepanov "Human expiration content diagnostics by tunable diode lasers in middle infrared", Proc. SPIE 1724, Tunable Diode Laser Applications, (1 April 1992); https://doi.org/10.1117/12.58677

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