Detection and quantification of thermal injury to the myocardium using ultrasound

Stephan E. Friedl; Yishin Weng; Eric D. Mathews; George S. Abela M.D.

doi:10.1117/12.137322

28 August 1992 Detection and quantification of thermal injury to the myocardium using ultrasound

Stephan E. Friedl, Yishin Weng, Eric D. Mathews, George S. Abela M.D.

Proceedings Volume 1642, Diagnostic and Therapeutic Cardiovascular Interventions II; (1992) https://doi.org/10.1117/12.137322
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

Selective thermal coagulation of discrete portions of the myocardium is becoming an accepted method for the treatment of various supraventricular tachyarrhythmias. This paper investigates the use of conventional ultrasonography for the detection and measurement of thermally coagulated lesions in myocardial tissue. Lesions were created in necropsied canine myocardium using a side-emitting laser catheter delivering cw Nd:YAG laser energy. Following irradiation, the sites were scanned with a 20 Mhz ultrasound catheter and the maximum depth of thermal damage was measured from the ultrasonographic imagery. The surface dimensions and transmural depth of thermal damage was then measured morphometrically with a video microscopy system. Depth measured by ultrasound was found to correlate well with depth by morphometry (r equals 0.78). Both depth measured by morphometry and by ultrasound were found to correlate well with the volume of thermal damage by morphometry (r equals 0.83 and r equals 0.77 respectively). Intraventricular ultrasonography may prove useful for in-vivo detection and measurement of thermally induced lesions in the myocardium. Additionally, it may also be applied for guidance and real-time monitoring of thermal coagulation of the myocardium during various arrhythmia ablation procedures.

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Stephan E. Friedl, Yishin Weng, Eric D. Mathews, and George S. Abela M.D. "Detection and quantification of thermal injury to the myocardium using ultrasound", Proc. SPIE 1642, Diagnostic and Therapeutic Cardiovascular Interventions II, (28 August 1992); https://doi.org/10.1117/12.137322

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KEYWORDS

Ultrasonography

Tissues

Injuries

Natural surfaces

Ultrasonics

In vivo imaging

Laser tissue interaction

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