Analysis of laser-induced vascular injury using image processing and 3D reconstruction

Cynthia J. Roberts; Xia Li

doi:10.1117/12.142579

28 August 1992 Analysis of laser-induced vascular injury using image processing and 3D reconstruction

Cynthia J. Roberts, Xia Li

Proceedings Volume 1642, Diagnostic and Therapeutic Cardiovascular Interventions II; (1992) https://doi.org/10.1117/12.142579
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

A new method is described for the quantitative evaluation of the extent of in vitro laser- induced arterial injury with computer assisted image processing techniques and 3-D reconstruction of histologic sections. Using this approach, accurate measurements of ablated volume and thermally injured volume may be obtained, along with a detailed description of crater shape, symmetry (or lack thereof), and 3-D distribution of residual thermal injury. The reconstructed injury may be rotated to view from various angles, or zoomed to greater magnification. Examination of the total crater may provide insight into damage mechanisms, as well as provide a more accurate assessment of arterial injury which may have important implications on the long term healing response.

Citation Download Citation

Cynthia J. Roberts and Xia Li "Analysis of laser-induced vascular injury using image processing and 3D reconstruction", Proc. SPIE 1642, Diagnostic and Therapeutic Cardiovascular Interventions II, (28 August 1992); https://doi.org/10.1117/12.142579

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