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4 October 2024 Recent advances in laboratory liquid-jet x-ray tomography for biomedical applications
Hans M. Hertz
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Proceedings Volume 13152, Developments in X-Ray Tomography XV; 131520L (2024) https://doi.org/10.1117/12.3027982
Event: Optical Engineering + Applications, 2024, San Diego, California, United States
Abstract
The liquid-metal-jet microfocus source presently provides a 5 to 25µm x-ray spot with up to 1kW e-beam power. This source enables several biomedical imaging applications where high spatial resolution, high contrast and short exposure time are critical. Examples: Cellular-resolution phase-contrast imaging for virtual x-ray histology as well as for clinical resection margin assessment, potentially with rapid intraoperative feedback. Preclinical in-vivo phase-contrast small-animal lung imaging and a path towards clinical phase-contrast medical imaging. Finally, x-ray fluorescence tomography for high-resolution molecular detection of tumors in live mice.
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Hans M. Hertz "Recent advances in laboratory liquid-jet x-ray tomography for biomedical applications", Proc. SPIE 13152, Developments in X-Ray Tomography XV, 131520L (4 October 2024); https://doi.org/10.1117/12.3027982
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KEYWORDS
X-rays
Biomedical applications
Tomography
Nanoparticles
Biomedical optics
Cancer detection
Image resolution
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