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6 November 2023 RAMAN spectroscopy for drug analysis
Tian Ma, Hang-hang Zheng, Qi Liao
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Proceedings Volume 12921, Third International Computing Imaging Conference (CITA 2023); 129212H (2023) https://doi.org/10.1117/12.2690466
Event: Third International Computing Imaging Conference (CITA 2023), 2023, Sydney, Australia
Abstract
Raman spectroscopy has become a hot research topic in the field of drug detection due to its non-destructive, rapid, non-polluting and flexible measurement methods. This article mainly summarizes the excellent detection performance of Raman spectroscopy in identifying new psychoactive substances, structurally similar substances and trace drugs (such as drug metabolites in blood and urine in living organisms) in the literature, demonstrates that Raman spectroscopy combined with chemometrics achieves excellent classification and identification of drugs, and introduces the application of Raman in combination with other techniques for the analysis of drug mixtures. In the future, based on the traditional generation one and generation two drugs, it is necessary to further improve the standard spectral library of generation three of New Psychoactive Substances (NPS) and the drug-making precursors, and to strengthen the design of surface-enhanced reagents, optimization of metrological algorithms, and in-depth research on the coupling techniques, so as to better serve the front-line anti-drug work and provide technical support for the on-site rapid detection of drugs.
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Tian Ma, Hang-hang Zheng, and Qi Liao "RAMAN spectroscopy for drug analysis", Proc. SPIE 12921, Third International Computing Imaging Conference (CITA 2023), 129212H (6 November 2023); https://doi.org/10.1117/12.2690466
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KEYWORDS
Raman spectroscopy
Surface enhanced Raman spectroscopy
Statistical analysis
Spectroscopy
Chemical analysis
Principal component analysis
Psychoactive substances
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