The application of three nanomaterials-based treatment methods for breast cancer

Xinyu Ming

doi:10.1117/12.2637337

10 June 2022 The application of three nanomaterials-based treatment methods for breast cancer

Xinyu Ming

Proceedings Volume 12179, Second International Conference on Medical Imaging and Additive Manufacturing (ICMIAM 2022); 121790N (2022) https://doi.org/10.1117/12.2637337
Event: Second International Conference on Medical Imaging and Additive Manufacturing (ICMIAM 2022), 2022, Xiamen, China

Abstract

Breast cancer has become a high incidence of cancer in women. The detection of breast cancer has become more and more important in recent years. A diverse of different treatment methods have widely used to detect breast cancer. The existing detection methods shows their own advantages and disadvantages. For example, the traditional chemotherapy has many side effects and great harm, which has seriously affected the quality of life of patients. The development of new cancer treatment methods has received increasing attention. Therefore, cancer treatment methods based on nanomaterials have been introduced, and good treatment effects have been achieved. This research describes three improved methods based on different nanomaterials that can replace chemotherapy. One is to improve trans-ferulic acid’s (TFA) efficiency by loading folate-receptor-targeted-poly lactic-co-glycolic acid nanoparticles (FA-PLGA-TFA NPs). Dox/FA-PLGA-TFA NPs reduced the side-effects of drugs, and at the same time showed superior anti-cancer performance and safety profile. The other is synthesized with biodegradable chitosan nanoparticles (CSNPs), which can selectively release DOX in the environment of breast tumors. In addition, CSNPs surface was modified with polyethylene glycol (PEG) to enhance its circulation time in the blood. Through this targeted nano drug delivery platform, it can be used to control dose-dependent system toxicity of freely ingested DOX.

Citation Download Citation

Xinyu Ming "The application of three nanomaterials-based treatment methods for breast cancer", Proc. SPIE 12179, Second International Conference on Medical Imaging and Additive Manufacturing (ICMIAM 2022), 121790N (10 June 2022); https://doi.org/10.1117/12.2637337

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