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The purpose of the work was to demonstrate the possibility of optical diagnosis in the consideration of sexually transmitted infections in the development of inflammatory processes of the cervix using spectral and polarization methods. Comparison of cervical specimens with and without coilocytosis, irradiated with a range-shifted polarized radiation, showed significant differences in the values of linear dichroism and its spectral dependences. The difference between the coilocyte response characteristic in the range 400-420 nm was calculated using computer programs. As a result, the use of spectropolarization studies and the fluorescence method will improve the accuracy of patient selection for a costly procedure - high-carcinogenic DNA diagnostics of HPV by the standard method of polymerase chain reaction.
O. Peresunko,S. Yermolenko,N. Horodynska,Ch. Felde,Ju. Galushko,A. Dobosh, andO. Konovchuk
"Polarimetric differential diagnosis of sexually transmitted inflammatory processes of the cervix", Proc. SPIE 12126, Fifteenth International Conference on Correlation Optics, 121260Q (20 December 2021); https://doi.org/10.1117/12.2615513
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O. Peresunko, S. Yermolenko, N. Horodynska, Ch. Felde, Ju. Galushko, A. Dobosh, O. Konovchuk, "Polarimetric differential diagnosis of sexually transmitted inflammatory processes of the cervix," Proc. SPIE 12126, Fifteenth International Conference on Correlation Optics, 121260Q (20 December 2021); https://doi.org/10.1117/12.2615513