Optimum illumination wavelength for fluorescence spectroscopy of atheromatous plaque

Arthur F. Gmitro; Andrew L. Alexander; Carolyn M.C. Davenport; G. H. Manriquez

doi:10.1117/12.17583

1 July 1990 Optimum illumination wavelength for fluorescence spectroscopy of atheromatous plaque

Arthur F. Gmitro, Andrew L. Alexander, Carolyn M.C. Davenport, G. H. Manriquez

Author Affiliations +

Proceedings Volume 1201, Optical Fibers in Medicine V; (1990) https://doi.org/10.1117/12.17583
Event: OE/LASE '90, 1990, Los Angeles, CA, United States

Abstract

Seven illumination wavelengths from 270 to 364 nm were investigated for their ability to produce differences in the fluorescence spectra between normal aorta and atheromatous plaque. Differences in the spectra were evaluated using the Hotelling trace and ROC methods. The results indicate that large spectral differences and, therefore, good classification can be obtained with illumination in the range from about 304 to 334 nm and that the performance drops off rapidly on either end of the illumination range.

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Arthur F. Gmitro, Andrew L. Alexander, Carolyn M.C. Davenport, and G. H. Manriquez "Optimum illumination wavelength for fluorescence spectroscopy of atheromatous plaque", Proc. SPIE 1201, Optical Fibers in Medicine V, (1 July 1990); https://doi.org/10.1117/12.17583

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