In this study, we compared the photothermal effects induced by the pulsed lasers including a fractional CO2 laser (=10600 nm) and a nanosecond Nd:YAG laser (=1064 nm). To investigate the induced photothermal effect, a spectral-domain optical coherence tomography (SD-OCT) system with a central wavelength of 840 nm was used to acquire 3D images of skin before and after the laser treatment. From the OCT results, the microscopic ablation zone (MAZ) resulted from the fractional CO2 laser can be identified that caused a stripe-shape photodamage on skin, ranging from the epidermis layer to the dermis layer. In contrast, the intra-dermal laser-induced optical breakdown (LIOB) induced by the nanosecond pulsed laser can also be observed from the OCT results.
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