Extraction of phase-based optoretinograms (ORG) from mouse retinal raster scanning OCT system

Ewelina Pijewska; Pengfei Zhang; Michal Meina; Maciej Szkulmowski; Robert Zawadzki

doi:10.1117/12.2577811

5 March 2021 Extraction of phase-based optoretinograms (ORG) from mouse retinal raster scanning OCT system

Ewelina Pijewska, Pengfei Zhang, Michal Meina, Maciej Szkulmowski, Robert Zawadzki

Proceedings Volume 11630, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXV; 1163008 (2021) https://doi.org/10.1117/12.2577811
Event: SPIE BiOS, 2021, Online Only

Abstract

Recent OCT based investigations in humans and in experimental animals have shown that rods and cones outer segments elongate in response to light stimuli. In this manuscript we describe our efforts to implement phase-based “optoretinograms” (ORG) analysis framework to retinal images acquired with standard raster scanning FD-OCT system, that offers much lower phase stability compared to full field or line field OCT acquisition schemes. Our initial results, acquired in anesthetized mice in vivo, showcase successful extraction of phase-based ORG signal and its favorable comparison with intensity-based ORG signal extracted from the same data sets.

Conference Presentation

Citation Download Citation

Ewelina Pijewska, Pengfei Zhang, Michal Meina, Maciej Szkulmowski, and Robert Zawadzki "Extraction of phase-based optoretinograms (ORG) from mouse retinal raster scanning OCT system", Proc. SPIE 11630, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXV, 1163008 (5 March 2021); https://doi.org/10.1117/12.2577811

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