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Speckle contrast optical spectroscopy (SCOS) allows for simultaneous monitoring of blood flow and volume changes within each cardiac pulse. SCOS measurements were collected from 13 subjects and blood flow and volume pulse waveforms (PWFs) were extracted. The correlations between features extracted from the PWFs and blood pressure before and after an exercise activity were investigated. We found that the time delay between the blood flow and volume peaks was strongly correlated with changes in blood pressure (R = -0.73), suggesting that the combination of blood flow and volume information may improve blood pressure estimation.
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Ariane Garrett, Kenny Kim, Jacob Chin, Edbert Sie, Francesco Marsili, David Boas, Darren Roblyer, "Preliminary investigation of non-invasive blood pressure estimation using speckle contrast optical spectroscopy," Proc. SPIE PC12363, Multiscale Imaging and Spectroscopy IV, PC123630M (17 March 2023); https://doi.org/10.1117/12.2651575