Dr. Ted A. Laurence Profile

Dr. Ted A. Laurence

at Lawrence Livermore National Lab

SPIE Involvement:

Author

Publications (19)

Proceedings Article | 13 March 2024 Presentation + Paper

Ghost imaging using two SPAD array detectors: a parameter study towards the realization of a 3D quantum microscope

Dominique Davenport, Audrey Eshun, Brandon Demory, Paul Mos, Lin Yang, Sam Jeppson, Ashleigh Wilson, Shervin Kiannejad, Tiziana Bond, Mike Rushford, Chuck Boley, Edoardo Charbon, Claudio Bruschini, Ted Laurence

Proceedings Volume 12863, 1286307 (2024) https://doi.org/10.1117/12.3002965

KEYWORDS: Single photon avalanche diodes, Quantum ghost imaging, Microscopes, Quantum entanglement, Sensors, Crystals, Image filtering

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Proceedings Article | 13 March 2024 Presentation + Paper

Investigating fluorescent amino acids with entangled two-photon excited fluorescence

Audrey Eshun, Ashleigh Wilson, Megan Shelby, Dominique Davenport, Sam Jeppson, Brandon Demory, Shervin Kiannejad, Charles Boley, Mike Rushford, Tiziana Bond, Ted Laurence

Proceedings Volume 12863, 1286306 (2024) https://doi.org/10.1117/12.3003307

KEYWORDS: Light absorption, Photon counting, Proteins, Fluorescence, Quantum entanglement, Ultraviolet radiation, Fluorescence imaging

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Fluorescence microscopy has become integral to biological studies for the technique’s ability to elucidate structures of biomolecules for in-situ studies with high selectivity and specificity. Imaging of intrinsic indicators, such as fluorescent amino acids in proteins, provides important information, but can be challenging to accomplish. Current microscopy techniques that measure native fluorescence without the use of exogenous labels involve either direct UV excitation which is commonly non-localized and can be detrimental to the system, or multiphoton absorption which must be conducted at high intensities, therefore posing high risks of photodamage. As such, we seek to investigate an efficient way to gently excite native fluorescence in biological systems in a way that overcomes these limitations. Quantum entangled photon pairs generated via spontaneous parametric downconversion (SPDC), may be an alternative to conducting two-photon absorption (TPA) to excite fluorescence in amino acids without the high fluences currently used. These photon pairs are highly correlated in time. Thus, the arrival of one photon is simultaneously followed by the arrival of its sister photon. As a result, a molecule interacting with the photon pair should simultaneously absorb both photons, leading to a linear two-photon absorption rate, and the linearity of the two-photon process should dramatically reduce the light intensity necessary for TPA. Therefore, quantum entangled photon pairs offer the possibility of performing low intensity UV excitation using photons in the visible wavelength range. With this work, we generated and characterized entangled photons generated via SPDC, and investigated whether fluorescent amino acids can be excited, and the subsequent fluorescence induced with entangled two-photon absorption. Results show that much higher entangled two-photon rates than what are currently available are needed to measure significant signals with entangled two-photon excitation.

Proceedings Article | 24 November 2023 Presentation

Potential implications of environmental effects of ps and ns laser-induced damage for damage initiation mechanisms

Ted Laurence, C. Carr, Eyal Feigenbaum, Sonny Ly, Raluca Negres

Proceedings Volume PC12726, PC127260J (2023) https://doi.org/10.1117/12.2684097

KEYWORDS: Vacuum, Switching, Silica, Polarization, Laser induced damage, Oxygen, Picosecond phenomena, Laser optics, Pulsed laser operation

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Proceedings Article | 24 November 2023 Paper

Temporally and spatially resolved photoluminescence of laser-induced damage sites of fused silica

Jae Hyuck Yoo, Yoonsoo Rho, Christopher Miller, Robin Yancey, Ted Laurence, Christopher Carr

Proceedings Volume 12726, 127260O (2023) https://doi.org/10.1117/12.2683719

KEYWORDS: Confocal microscopy, Image visualization, Photoluminescence, Silica, Visualization, Reflection, Laser induced damage, National Ignition Facility, 3D image processing, Absorption

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Proceedings Article | 2 March 2022 Presentation

Wavefront shaping with Hadamard basis for soil imaging

Dongping Wang, Lisa Poyneer, Diana Chen, Sonny Ly, Ted Laurence, Jang Hyuk Lee, Mark Ammons, Peter Weber

Proceedings Volume PC11969, PC119690E (2022) https://doi.org/10.1117/12.2609790

KEYWORDS: Optical imaging, Visualization, Scattering, Opacity, Light scattering, Wavefronts, Zernike polynomials, Stochastic processes

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Proceedings Article | 5 March 2021 Presentation

Adaptive optics for imaging through soil minerals

Dongping Wang, Lisa Poyneer, Diana Chen, Sonny Ly, Ted Laurence, Jang Hyuk Lee, Mark Ammons, Peter Weber

Proceedings Volume 11652, 1165203 (2021) https://doi.org/10.1117/12.2576583

KEYWORDS: Image processing algorithms and systems, Microscopes, Minerals, Imaging systems, Scattering, Wavefronts, Adaptive optics, Spatial light modulators, Image quality, Wavefront distortions

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Proceedings Article | 5 March 2021 Presentation

Label-free multiphoton nonlinear microspectroscopy imaging of microbial cells and organic matter in rhizosphere and soil minerals

Janghyuk Lee, Sonny Ly, Ted Laurence, Peter Weber

Proceedings Volume 11655, 116550K (2021) https://doi.org/10.1117/12.2577311

KEYWORDS: Confocal microscopy, Minerals, Multiphoton microscopy, Microscopy, Luminescence, Imaging spectroscopy, Raman spectroscopy, Third-harmonic generation, Multiphoton fluorescence microscopy

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Proceedings Article | 11 September 2020 Presentation

Rapid non-destructive detection of defects in bulk and epitaxially grown GaN

Selim Elhadj, Jake Yoo, Ted Laurence, Qinghui Shao, Sonny Ly, Lars Voss, Matthias Daemeur

Proceedings Volume 11514, 115140M (2020) https://doi.org/10.1117/12.2571660

KEYWORDS: Semiconductors, Electronics, Defect detection, Crystals, Reliability, Nondestructive evaluation, Imaging devices, Electronic components, Gallium nitride, Crystallography

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Proceedings Article | 16 November 2018 Paper

Novel etching fluids for potassium dihydrogen phosphate

Salmaan Baxamusa, John Adams, Paul Ehrmann, Steven Hawks, Ted Laurence, Marlon Menor, Jemi Ong, Kathleen Schaffers

Proceedings Volume 10805, 108051G (2018) https://doi.org/10.1117/12.2500297

KEYWORDS: Potassium, Etching, Laser induced damage, Luminescence, Crystals, Resistance, Optical activity, Laser damage threshold

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Proceedings Article | 22 February 2017 Paper

Using stroboscopic flow imaging to validate large-scale computational fluid dynamics simulations

Ted Laurence, Sonny Ly, Erika Fong, Maxim Shusteff, Amanda Randles, John Gounley, Erik Draeger

Proceedings Volume 10076, 100761E (2017) https://doi.org/10.1117/12.2253319

KEYWORDS: Computational fluid dynamics, Biomedical optics, Computational modeling, Tumors, Modulation, Cameras, Blood, Image processing, Luminescence, Computer simulations, Image analysis, Data acquisition, Biological research, Velocity measurements, Spectroscopes, Fluid dynamics

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Proceedings Article | 1 March 2016 Presentation + Paper

Photon-HDF5: open data format and computational tools for timestamp-based single-molecule experiments

Antonino Ingargiola, Ted Laurence, Robert Boutelle, Shimon Weiss, Xavier Michalet

Proceedings Volume 9714, 971405 (2016) https://doi.org/10.1117/12.2212085

KEYWORDS: MATLAB, Computer programming, Software development, Resonance energy transfer, Open source software, Fluorescence correlation spectroscopy, Fluorescence resonance energy transfer, Data conversion, Atmospheric particles, Electroluminescent displays, Binary data, Single molecule spectroscopy, Computer programming languages, Single-photon counters

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Proceedings Article | 23 November 2015 Paper

Multipulse degradation of fused silica surfaces at 351 nm

Sonny Ly, Ted Laurence, Nan Shen, Bill Hollingsworth, Mary Norton, Jeff Bude

Proceedings Volume 9632, 96320T (2015) https://doi.org/10.1117/12.2195595

KEYWORDS: Silica, Silicon, Coating, Oxygen, Sol-gels, 3D scanning, Laser beam diagnostics, Laser optics, Pulsed laser operation, Absorption

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Proceedings Article | 23 November 2015 Paper

Characterization of laser-induced damage by picosecond pulses on multi-layer dielectric coatings for petawatt-class lasers

Raluca Negres, Christopher Carr, Isaac Bass, David Alessi, Ted Laurence, Ken Stanion, Gabe Guss, David Cross, Paul Wegner, Christopher Stolz

Proceedings Volume 9632, 963206 (2015) https://doi.org/10.1117/12.2195528

KEYWORDS: Calibration, Laser induced damage, Laser energy, Dielectrics, Resistance, Optical coatings, Inspection, Raster graphics, Picosecond phenomena, Laser beam diagnostics, Thin film deposition, Pulsed laser operation, Optical materials characterization, National Ignition Facility, Laser-matter interactions, Laser systems engineering

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Proceedings Article | 31 October 2014 Open Access

Silica laser damage mechanisms, precursors, and their mitigation

J. Bude, P. Miller, N. Shen, T. Suratwala, T. Laurence, W. Steele, S. Baxamusa, L. Wong, W. Carr, D. Cross, M. Monticelli, M. Feit, G. Guss

Proceedings Volume 9237, 92370S (2014) https://doi.org/10.1117/12.2070017

KEYWORDS: Atrial fibrillation, Silica, Etching, Glasses, Laser induced damage, Laser damage threshold, National Ignition Facility, Surface finishing, Temperature metrology, Absorption

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Proceedings Article | 4 December 2012 Paper

Correlation of UV damage threshold with post-annealing in CVD-grown SiO[sub]2[/sub] overlayers on etched fused silica substrates

Manylibo Matthews, Nan Shen, Selim Elhadj, Phillip Miller, A. Nelson, Ted Laurence, Julie Hamilton

Proceedings Volume 8530, 85300B (2012) https://doi.org/10.1117/12.979210

KEYWORDS: FT-IR spectroscopy, Laser therapeutics, Silica, Laser induced damage, Ultraviolet radiation, Annealing, Reflectivity, Carbon dioxide lasers, Chemical vapor deposition, Laser damage threshold

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SPIE Journal Paper | 10 October 2012 Open Access

Thermal annealing of laser damage precursors on fused silica surfaces

Nan Shen, Philip Miller, Jeffrey Bude, Ted Laurence, Tayyab Suratwala, William Steele, Michael Feit, Lana Wong

OE, Vol. 51, Issue 12, 121817, (October 2012) https://doi.org/10.1117/12.10.1117/1.OE.51.12.121817

KEYWORDS: Annealing, Silica, Laser damage threshold, Laser induced damage, Surface finishing, Glasses, Optical damage, Absorption, Polishing, Luminescence

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Proceedings Article | 31 December 2009 Paper

Laser damage precursors in fused silica

P. Miller, T. Suratwala, J. Bude, T. Laurence, N. Shen, W. Steele, M. Feit, J. Menapace, L. Wong

Proceedings Volume 7504, 75040X (2009) https://doi.org/10.1117/12.836986

KEYWORDS: Confocal microscopy, Optical components, Polishing, Silica, Etching, Laser induced damage, Luminescence, Laser damage threshold, Cerium, Surface finishing

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Proceedings Article | 31 December 2009 Paper

Ultrafast photoluminescence as a diagnostic for laser damage initiation

Ted Laurence, Jeff Bude, Nan Shen, Phillip Miller, William Steele, Gabe Guss, John Adams, Lana Wong, Michael Feit, Tayyab Suratwala

Proceedings Volume 7504, 750416 (2009) https://doi.org/10.1117/12.836923

KEYWORDS: Confocal microscopy, Silica, Laser induced damage, Luminescence, Laser scattering, Carbon dioxide lasers, Laser damage threshold, Pulsed laser operation, Surface finishing, Absorption

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Proceedings Article | 19 October 2004 Paper

Application of SERS nanoparticles for intracellular pH measurements

Ted Laurence, Chad Talley, Michael Colvin, Thomas Huser

Proceedings Volume 5512, (2004) https://doi.org/10.1117/12.559562

KEYWORDS: Confocal microscopy, Nanoparticles, Particles, Molecules, Diffusion, Silver, Surface enhanced Raman spectroscopy, Raman spectroscopy, Spatial resolution, Signal detection

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Showing 5 of 19 publications

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