Preliminary design of a handheld spatial frequency domain imager for quantitative scleroderma skin assessment

Aarohi Mehendale; Kavon Karrobi; Anahita Pilvar; Andreea Bujor; Darren Roblyer

doi:10.1117/12.2691936

13 March 2024 Preliminary design of a handheld spatial frequency domain imager for quantitative scleroderma skin assessment

Aarohi Mehendale, Kavon Karrobi, Anahita Pilvar, Andreea Bujor, Darren Roblyer

Author Affiliations +

Proceedings Volume PC12827, Multiscale Imaging and Spectroscopy V; PC1282709 (2024) https://doi.org/10.1117/12.2691936
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Our prior work has established that SFDI metrics can be used to assess skin involvement in scleroderma. To ease clinical translation of SFDI for SSc disease assessment, a preliminary design for a handheld SFDI system optimized for measurement of sclerodermatous skin is proposed. An LED is used as an illumination source, light is modulated using a printed transparency, and Rd is extracted using single snapshot demodulation methods. Additionally, the imager can measure scattering orientation using a rotating pattern. The performance of the imager was assessed using phantoms, and its inter- and intra-observer reliabilities were assessed.

Conference Presentation

Citation Download Citation

Aarohi Mehendale, Kavon Karrobi, Anahita Pilvar, Andreea Bujor, and Darren Roblyer "Preliminary design of a handheld spatial frequency domain imager for quantitative scleroderma skin assessment", Proc. SPIE PC12827, Multiscale Imaging and Spectroscopy V, PC1282709 (13 March 2024); https://doi.org/10.1117/12.2691936

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