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7 March 2023 Multi-wavelength multi-distance diffuse correlation spectroscopy system for assessment of premature infants’ cerebral hemodynamics
Nikola Otic, John Sunwoo, Yujing Huang, Alyssa Martin, Mitchell B. Robinson, Bernhard Zimmermann, Stefan A. Carp, Maria A. Franceschini, Marco Renna
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Proceedings Volume PC12376, Optical Tomography and Spectroscopy of Tissue XV; PC123760E (2023) https://doi.org/10.1117/12.2649662
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
Infants born at an extremely low gestational age are at an increased risk of intraventricular hemorrhaging during the first three postnatal days. We have built a standalone easy-to-use multi-wavelength multi-distance diffuse correlation spectroscopy system, which utilizes three time-multiplexed long coherence lasers at 785, 808, and 853 nm, single photon detectors, and photon time-tagging electronics to simultaneously quantify cerebral blood flow, tissue optical properties, and blood oxygen saturation. The system has been designed specifically for use on preterm infants. The device shows good agreement with a commercially available NIRS-DCS system. We are currently monitoring preterm infants and will show results.
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Nikola Otic, John Sunwoo, Yujing Huang, Alyssa Martin, Mitchell B. Robinson, Bernhard Zimmermann, Stefan A. Carp, Maria A. Franceschini, and Marco Renna "Multi-wavelength multi-distance diffuse correlation spectroscopy system for assessment of premature infants’ cerebral hemodynamics", Proc. SPIE PC12376, Optical Tomography and Spectroscopy of Tissue XV, PC123760E (7 March 2023); https://doi.org/10.1117/12.2649662
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KEYWORDS
Hemodynamics
Spectroscopy
Near infrared spectroscopy
Mode conditioning cables
Multiplexing
Optical properties
Photodetectors
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