Correlation mapping method of OCT for visualization blood vessels in brain

O. A. Izotova; A. L. Kalyanov; V. V. Lychagov; O. V. Semyachkina-Glushkovskaya

doi:10.1117/12.2044701

18 November 2013 Correlation mapping method of OCT for visualization blood vessels in brain

O. A. Izotova, A. L. Kalyanov, V. V. Lychagov, O. V. Semyachkina-Glushkovskaya

Proceedings Volume 9032, Biophotonics—Riga 2013; 90320G (2013) https://doi.org/10.1117/12.2044701
Event: 1st International Conference "Biophotonics Riga 2013", 2013, Riga, Latvia

Abstract

The burning issue in modern medicine is the diagnosis and treatment of various life-threatening diseases, in particular the diseases of brain. One of them is intracranial hemorrhage (ICH). It occurs especially among newborn babies and is hard-diagnosed. In order to understand the nature of the ICH, the microcirculation of blood, which serves key functions within the body, is analyzed. On this basis a series of experiments was done, in the results of which it was showed, that latent stage of ICH is characterized by decrease of venous blood outflow and the loss of sensitivity of sagittal vein to vasoconstrictor effect of adrenaline. So, stress-related changes of the cerebral venous blood flow (CVBF) can be the source of this disease. In this paper registration CVBF was made with the help of commercially available Thorlabs Swept Source OCT System, using the correlation mapping method. In this method values of correlation coefficient of several images are analyzed. In the result of the algorithm the correlation map was obtained. By the resulting map the diameter of vessels was calculated, which is necessary for examination of effects of adrenalin to the vessels and identification symptoms of ICH.

Citation Download Citation

O. A. Izotova, A. L. Kalyanov, V. V. Lychagov, and O. V. Semyachkina-Glushkovskaya "Correlation mapping method of OCT for visualization blood vessels in brain", Proc. SPIE 9032, Biophotonics—Riga 2013, 90320G (18 November 2013); https://doi.org/10.1117/12.2044701

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