In-vivo human retinal imaging with pulsed illumination spectral-domain optical coherence tomography

Jang-Woo You; Teresa C. Chen; Mircea Mujat; B. Hyle Park; Johannes F. de Boer

doi:10.1117/12.701240

7 February 2007 In-vivo human retinal imaging with pulsed illumination spectral-domain optical coherence tomography

Jang-Woo You, Teresa C. Chen, Mircea Mujat, B. Hyle Park, Johannes F. de Boer

Proceedings Volume 6429, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XI; 642912 (2007) https://doi.org/10.1117/12.701240
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

We present pulsed illumination spectral-domain optical coherence tomography (SD-OCT) for in vivo human retinal imaging. We analyze the signal-to-noise (SNR) for continuous wave (CW) and pulsed illumination SD-OCT. The lateral beam scan motion is responsible for a SNR drop due to lateral scanning induced interference fringe washout. Pulsed illumination can reduce the SNR drop by shorter sample illumination time during the integration time of a camera. First, we demonstrate the SNR benefit of pulsed illumination over CW as function of lateral scan speed for a paper sample. For in-vivo human retinal imaging with pulsed illumination, the maximum permissible exposure (MPE) according to pulse repetition rate is presented based on ANSI standard. Finally, we show better SNR in retinal images of a normal subject with pulsed illumination SD-OCT over CW at high lateral scanning speed.

Citation Download Citation

Jang-Woo You, Teresa C. Chen, Mircea Mujat, B. Hyle Park, and Johannes F. de Boer "In-vivo human retinal imaging with pulsed illumination spectral-domain optical coherence tomography", Proc. SPIE 6429, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XI, 642912 (7 February 2007); https://doi.org/10.1117/12.701240

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