Model predictions and measured skin damage thresholds for 1.54-&mu;m laser pulses in porcine skin

William P. Roach; James J. Thomas; Kurt J. Schuster; Kevin Stockton; David J. Stolarski; Michael S. Foltz; Benjamin A. Rockwell; Clarence P. Cain

doi:10.1117/12.477656

27 August 2003 Model predictions and measured skin damage thresholds for 1.54-μm laser pulses in porcine skin

William P. Roach, James J. Thomas, Kurt J. Schuster, Kevin Stockton, David J. Stolarski, Michael S. Foltz, Benjamin A. Rockwell, Clarence P. Cain

Author Affiliations +

Proceedings Volume 4961, Laser-Tissue Interaction XIV; (2003) https://doi.org/10.1117/12.477656
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

A thermal model was used to calculate the skin temperature rise in porcine skin and predict the damage thresholds in terms of laser power for various wavelengths, pulse durations, skin parameters and laser spot sizes. Laser exposures of 1.54 μm, 0.60 ms in duration and using a 0.7 mm spot size were applied to the porcine skin. The damage thresholds were determined at 1-hour and 24-hour post exposures using probit analysis. Only one subject was exposed giving adequate fiducial limits at the 95% confidence level. The ED50 for these 72 exposures was determined to be 58 mJ, giving a radiant exposure of 15 Jcm^-2. The damage threshold is compared with model predictions, with work previously published in the literature and with the ANSI Standard’s MPE for 1540 nm lasers at 0.60 ms.

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William P. Roach, James J. Thomas, Kurt J. Schuster, Kevin Stockton, David J. Stolarski, Michael S. Foltz, Benjamin A. Rockwell, and Clarence P. Cain "Model predictions and measured skin damage thresholds for 1.54-μm laser pulses in porcine skin", Proc. SPIE 4961, Laser-Tissue Interaction XIV, (27 August 2003); https://doi.org/10.1117/12.477656

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