Optimizing image reconstruction of tissue blood flow by diffuse correlation tomography

Chao Zhou; Turgut Durduran; Guoqiang Yu; Arjun G. Yodh

doi:10.1117/12.476883

29 July 2003 Optimizing image reconstruction of tissue blood flow by diffuse correlation tomography

Chao Zhou, Turgut Durduran, Guoqiang Yu, Arjun G. Yodh

Proceedings Volume 4955, Optical Tomography and Spectroscopy of Tissue V; (2003) https://doi.org/10.1117/12.476883
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

In this work, we analyze the image reconstruction problem within the first order Rytov approximation and optimize the image reconstruction by looking at the singular value spectrum of the "weight matrix". We show that the optimal data is from the tail of the temporal intensity autocorrelation curve by investigating the condition number. Furthermore, by doing a standard L-curve analysis, we find the optimal regularization constant (Tikhonov regularization). Images from simulated data are shown to illustrate the advantage of the optimization process.

Citation Download Citation

Chao Zhou, Turgut Durduran, Guoqiang Yu, and Arjun G. Yodh "Optimizing image reconstruction of tissue blood flow by diffuse correlation tomography", Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); https://doi.org/10.1117/12.476883

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