Near-infrared spectroscopy of the human brain during electroconvulsive therapy

Sergio Fantini; Francesco Fabbri; Shalini Nadgir; Michael E. Henry; Perry F. Renshaw; Maria-Angela Franceschini

doi:10.1117/12.478131

29 July 2003 Near-infrared spectroscopy of the human brain during electroconvulsive therapy

Sergio Fantini, Francesco Fabbri, Shalini Nadgir, Michael E. Henry, Perry F. Renshaw, Maria-Angela Franceschini

Proceedings Volume 4955, Optical Tomography and Spectroscopy of Tissue V; (2003) https://doi.org/10.1117/12.478131
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

We report non-invasive, bilateral measurements of cerebral oxygenation performed with near-infrared spectroscopy (NIRS) on ten patients undergoing right unilateral electro-convulsive therapy (ECT). Right unilateral ECT consists of delivering an electrical current through the right brain hemisphere to induce a seizure, which is associated with significant changes in systemic and regional physiological parameters. In this work, we have examined the regional cerebral oxygenation (StO₂) measured with NIRS on the right and left sides of the frontal brain region, and the systemic arterial oxygenation (SaO₂) measured with pulse oximetry. On the ten patients examined, we have found that the decrease in the cerebral oxygenation on the side ipsilateral to the ECT electrical discharge (ΔStO₂^(ipsi)) is consistently stronger than the decrease on the contralateral side (ΔStO₂^(contra)). The average and standard deviation for the ipsilateral and contralateral oxygenation changes across the ten patients are ΔStO₂^(ipsi) = -22 ± 10% and ΔStO₂^(contra) = -6 ± 10%, respectively. By contrast, we observed two distinct behaviors in the arterial saturation; in five patients, SaO₂ did not significantly change during the ECT procedure, and in three patients, SaO₂ decreased by -16± 6%, an intermediate value with respect to the changes observed in StO₂^(ipsi)and StO₂^(contra) (we do not have the SaO₂ recording in the remaining two patients for technical reasons). These results indicate that NIRS monitoring of the cerebral oxygenation during ECT has the potential of being a valuable addition to the standard monitoring of arterial saturation with pulse oximetry.

Citation Download Citation

Sergio Fantini, Francesco Fabbri, Shalini Nadgir, Michael E. Henry, Perry F. Renshaw, and Maria-Angela Franceschini "Near-infrared spectroscopy of the human brain during electroconvulsive therapy", Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); https://doi.org/10.1117/12.478131

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
5 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Near infrared spectroscopy

Brain

Oximetry

Oximeters

Tissue optics

Electrodes

Electroencephalography

Show All Keywords

Keywords/Phrases

Search In:

Publication Years