Optoacoustic supercontrast for early cancer detection

Alexander A. Karabutov; Elena V. Savateeva; Alexander A. Oraevsky

doi:10.1117/12.429306

15 June 2001 Optoacoustic supercontrast for early cancer detection

Alexander A. Karabutov, Elena V. Savateeva, Alexander A. Oraevsky

Proceedings Volume 4256, Biomedical Optoacoustics II; (2001) https://doi.org/10.1117/12.429306
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

Thermal mechanism is fundamental for the generation of ultrasonic waves in a course of absorption of laser radiation. Its efficiency is relatively low, but increases significantly with temperature (thermal non-linearity). If the phase transition of the irradiated medium occur, the efficiency may exceed its linear regime value several orders of magnitude. The idea of optoacoustic supercontrast for early cancer detection is based on this fact. We performed feasibility studies and describe requirements to and properties of the optoacoustic supercontrast agent based on nanoscopid particles. The results of the preliminary experiments with the metal and carbon nanoparticles as optoacoustic generation up to three orders of magnitude under irradiation conditions of laser optoacoustic imaging in the depth of human tissue.

Citation Download Citation

Alexander A. Karabutov, Elena V. Savateeva, and Alexander A. Oraevsky "Optoacoustic supercontrast for early cancer detection", Proc. SPIE 4256, Biomedical Optoacoustics II, (15 June 2001); https://doi.org/10.1117/12.429306

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