Use of chloro-aluminum sulfonated phthalocyanine as a photosensitizer in the treatment of malignant tumors in dogs and cats

George M. Peavy D.V.M.; Mary Kay Klein; H. Carlton Newman D.V.M.; Walter Gregory Roberts; Michael W. Berns

doi:10.1117/12.44004

1 May 1991 Use of chloro-aluminum sulfonated phthalocyanine as a photosensitizer in the treatment of malignant tumors in dogs and cats

George M. Peavy D.V.M., Mary Kay Klein, H. Carlton Newman D.V.M., Walter Gregory Roberts, Michael W. Berns

Author Affiliations +

Proceedings Volume 1424, Lasers in Orthopedic, Dental, and Veterinary Medicine; (1991) https://doi.org/10.1117/12.44004
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

Chloro-aluminum sulfonated phthalocyanine (CASPc) has been proposed as a photosensitizing agent for photodynamic therapy (PDT) of neoplasia. This paper reviews the results of PDT treatment using CASPc as a photosensitizing agent in the treatment of 15 cats representing 23 sites of facial, solar induced squamous cell carcinoma, 4 dogs with hemangiopericytomas, 3 dogs with fibrosarcomas, and 1 dog with multiple cutaneous mast cell tumors. The results of this study to date suggest that CASPc is a good photosensitizing agent for the treatment of some forms of spontaneously occurring malignant neoplasia and should be more thoroughly evaluated for this purpose.

Citation Download Citation

George M. Peavy D.V.M., Mary Kay Klein, H. Carlton Newman D.V.M., Walter Gregory Roberts, and Michael W. Berns "Use of chloro-aluminum sulfonated phthalocyanine as a photosensitizer in the treatment of malignant tumors in dogs and cats", Proc. SPIE 1424, Lasers in Orthopedic, Dental, and Veterinary Medicine, (1 May 1991); https://doi.org/10.1117/12.44004

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