5 March 2021Oxygen consumption in skeletal muscle using single-distance, multi-distance and dual-slope data from frequency-domain near-infrared spectroscopy
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The use of phase (Φ) data collected in Frequency-Domain Near-InfraRed Spectroscopy (FD-NIRS) has not been widespread in measurements of skeletal muscle and has mainly been applied to measure absolute optical properties. We show that single-distance (SD) Φ has a deeper sensitivity compared to SD intensity (I) and can be more sensitive to oxygen consumption in skeletal muscle underneath superficial adipose tissue. We also show the potential benefit of single-slope (SS) or dual-slope (DS) I or Φ in muscle studies.
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Cristianne Fernandez, Giles Blaney, Thao Pham, Angelo Sassaroli, Sergio Fantini, "Oxygen consumption in skeletal muscle using single-distance, multi-distance and dual-slope data from frequency-domain near-infrared spectroscopy," Proc. SPIE 11639, Optical Tomography and Spectroscopy of Tissue XIV, 116391M (5 March 2021); https://doi.org/10.1117/12.2578425