Presentation
20 August 2020 Improving spatial resolution in optogenetics using organic light-emitting diodes and smartphone displays
Author Affiliations +
Abstract
Optogenetics is a technique to modulate neuronal activity in response to light. Here, we present two different light sources that can provide high spatial resolution for precise optogenetic stimulation of Drosophila melanogaster (fruit fly) larvae: organic light-emitting diodes (OLEDs) and smartphone displays. Using micro-structured OLED arrays, we stimulated sensory neurons in individual abdominal segments of Drosophila larvae and thus controlled their crawling direction. Furthermore, we developed a smartphone app that allows spectral, spatial, and temporal control over the light emitted by the display and used this to deliver fine patterns of light to constrain larval movement.
Conference Presentation
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Caroline Murawski, Ilenia Meloni, Stefan R. Pulver, Andreas S. Thum, Robert J. Kittel, and Malte C. Gather "Improving spatial resolution in optogenetics using organic light-emitting diodes and smartphone displays", Proc. SPIE 11473, Organic and Hybrid Light Emitting Materials and Devices XXIV, 114730M (20 August 2020); https://doi.org/10.1117/12.2575600
Advertisement
Advertisement
KEYWORDS
Organic light emitting diodes

Optogenetics

Spatial resolution

Light sources

Sensors

Consumer electronics

Control systems

Back to Top