CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 11241 > Article
Presentation
6 March 2020 Polypyrrole nanoparticles as drug delivery and photothermal agents (Conference Presentation)
Connor L. West, Austin C. V. Doughty, Kaili Liu, Wei R. Chen
Author Affiliations +
Proceedings Volume 11241, Biophotonics and Immune Responses XV; 1124109 (2020) https://doi.org/10.1117/12.2549338
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
Laser Immunotherapy (LIT) is a novel treatment for metastatic cancer that uses laser irradiation and an immunostimulant to achieve lasting anti-tumor immunity. To increase photothermal conversion efficiency, LIT has used several types of agents tuned to absorb near-infrared (NIR) light. Polypyrrole (PPy) is an organic polymer with similar light absorbing characteristics to previously studied nanomaterials. We carried out dose-dependent PPy toxicity, stability, and photothermal experiments using a mouse breast cancer model. The marked stability under laser irradiation, coupled with PPy’s high photothermal conversion efficiency and low toxicity suggest that PPy could replace nanomaterials as a photothermal and drug-delivery agent.
Conference Presentation
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Connor L. West, Austin C. V. Doughty, Kaili Liu, and Wei R. Chen "Polypyrrole nanoparticles as drug delivery and photothermal agents (Conference Presentation)", Proc. SPIE 11241, Biophotonics and Immune Responses XV, 1124109 (6 March 2020); https://doi.org/10.1117/12.2549338
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Nanoparticles
Nanomaterials
Laser irradiation
Toxicity
Cancer
In vitro testing
Nanorods
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top