Sensorless adaptive optics optical coherence tomographic angiography (OCTA) of the retinal plexuses (Conference Presentation)

Acner Camino Benech; Pengxiao Zang; Yukun Guo; Ringo Ng; Joey Huang; Yali Jia; David Huang; Yifan Jian

doi:10.1117/12.2546884

9 March 2020 Sensorless adaptive optics optical coherence tomographic angiography (OCTA) of the retinal plexuses (Conference Presentation)

Acner Camino Benech, Pengxiao Zang, Yukun Guo, Ringo Ng, Joey Huang, Yali Jia, David Huang, Yifan Jian

Author Affiliations +

Proceedings Volume 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV; 112280V (2020) https://doi.org/10.1117/12.2546884
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

In OCTA, resolution of retinal capillaries is limited by physical numerical aperture of human eye and the subject’s ocular aberrations. Adaptive optics OCTA has been demonstrated in instruments with large numerical aperture, originally designed for the visualization of retinal cells. In this work, we propose a high-speed, spectral domain sensorless adaptive optics OCTA instrument with a 3-mm beam to image retinal capillaries of all three retinal plexuses simultaneously, with high axial and lateral resolution. A novel and fast hill climbing algorithm was applied on the amplitude of six low-order Zernike modes to minimize ocular aberrations based on maximizing en face merit functions of the layer of interest computed in real time.

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Acner Camino Benech, Pengxiao Zang, Yukun Guo, Ringo Ng, Joey Huang, Yali Jia, David Huang, and Yifan Jian "Sensorless adaptive optics optical coherence tomographic angiography (OCTA) of the retinal plexuses (Conference Presentation)", Proc. SPIE 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV, 112280V (9 March 2020); https://doi.org/10.1117/12.2546884

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KEYWORDS

Angiography

Sensors

Adaptive optics optical coherence tomography

Adaptive optics

Monochromatic aberrations

Capillaries

Eye

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